Fenticonazole
Clinical data | |
---|---|
Trade names | Lomexin, Gynoxin |
AHFS/Drugs.com | International Drug Names |
Routes of administration | Topical (ovule, spray, cream) |
ATC code | |
Legal status | |
Legal status |
|
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C24H20Cl2N2OS |
Molar mass | 455.40 g·mol−1 |
3D model (JSmol) | |
| |
| |
(what is this?) |
Fenticonazole is an imidazole antifungal drug, used locally as the nitrate in the treatment of vulvovaginal candidiasis. It is active against a range of organisms including dermatophyte pathogens, Malassezia furfur, and Candida albicans.
Uses and administration[]
A 200 mg pessary is inserted into the vagina at bedtime for 3 nights or a 600 mg pessary is inserted once only at bedtime. Fenticonazole nitrate is also applied topically as a 2% cream or solution for the treatment of fungal skin infections.
Adverse effects[]
Burning and itching have been reported after the application of fenticonazole nitrate.
Intravaginal preparations of fenticonazole may damage latex contraceptives and additional contraceptive measures are therefore necessary during local administration.
References[]
- The Merck Index, 12th Edition. 4047
Categories:
- Thioethers
- Ethers
- Chloroarenes
- Imidazole antifungals
- Lanosterol 14α-demethylase inhibitors
- Genito-urinary system drug stubs