Hepatic fructokinase
ketohexokinase (fructokinase) | |||||||
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![]() Ketohexokinase homodimer, Human | |||||||
Identifiers | |||||||
Symbol | KHK | ||||||
NCBI gene | 3795 | ||||||
HGNC | 6315 | ||||||
OMIM | 229800 | ||||||
RefSeq | NM_006488 | ||||||
UniProt | P50053 | ||||||
Other data | |||||||
EC number | 2.7.1.3 | ||||||
Locus | Chr. 2 p23.3-23.2 | ||||||
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Ketohexokinase | |||||||||
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Identifiers | |||||||||
EC no. | 2.7.1.3 | ||||||||
CAS no. | 9030-50-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Hepatic fructokinase (or ketohexokinase) is an enzyme that catalyzes the phosphorylation of fructose to produce fructose-1-phosphate.
Pathology[]
A deficiency is associated with essential fructosuria.
References[]
- ^ Bais R, James HM, Rofe AM, Conyers RA (1985). "The purification and properties of human liver ketohexokinase. A role for ketohexokinase and fructose-bisphosphate aldolase in the metabolic production of oxalate from xylitol". Biochem. J. 230 (1): 53–60. doi:10.1042/bj2300053. PMC 1152585. PMID 2996495.
External links[]
- Hepatic+fructokinase at the US National Library of Medicine Medical Subject Headings (MeSH)
Categories:
- Genes on human chromosome 2
- EC 2.7.1
- EC 2.7 stubs