Orestrate
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Other names | Estradiol 3-propionate 17β-(1-cyclohexenyl) ether; 17β-(Cyclohexen-1-yloxy)-estra-1,3,5(10)-trien-3-ol propionate |
Drug class | Estrogen; Estrogen ester |
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Formula | C27H36O3 |
Molar mass | 408.582 g·mol−1 |
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Orestrate (INN), also known as estradiol 3-propionate 17β-(1-cyclohexenyl) ether, is an estrogen medication and estrogen ester which was never marketed.[1][2][3][4][5] It is the C3 propionate ester and C17β-(1-cyclohexenyl) ether of estradiol.[1][5]
See also[]
- List of estrogen esters § Esters of steroidal estrogens
References[]
- ^ a b J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 898, 905. ISBN 978-1-4757-2085-3.
- ^ Gardi R, Vitali R, Falconi G, Ercoli A (February 1973). "1,3,5(10)-Estratrien-17 -yl enol ethers and acetals. New classes of orally and parenterally active estrogenic derivatives". J. Med. Chem. 16 (2): 123–7. doi:10.1021/jm00260a009. PMID 4683106.
- ^ Galletti F, Gardi R (April 1974). "Effect of two orally active estradiol derivatives on sulfobromphthalein retention in rats". Pharmacol Res Commun. 6 (2): 135–45. doi:10.1016/s0031-6989(74)80021-4. PMID 4438394.
- ^ P. H. List; L. Hörhammer (12 March 2013). Chemikalien und Drogen Teil A: N-Q. Springer-Verlag. pp. 331–. ISBN 978-3-642-65035-2.
- ^ a b Edward B. Roche; Academy of Pharmaceutical Sciences. Medicinal Chemistry Section (1977). Design of biopharmaceutical properties through prodrugs and analogs: a symposium. The Academy. p. 7. ISBN 978-0-917330-16-2.
Categories:
- Abandoned drugs
- Cyclohexenes
- Estradiol esters
- Estranes
- Estrogen ethers
- Synthetic estrogens
- Genito-urinary system drug stubs
- Steroid stubs