3-hydroxypimeloyl-CoA dehydrogenase

In enzymology, a 3-hydroxypimeloyl-CoA dehydrogenase (EC 1.1.1.259) is an enzyme that catalyzes the chemical reaction

3-hydroxypimeloyl-CoA + NAD⁺ ${\displaystyle \rightleftharpoons }$ 3-oxopimeloyl-CoA + NADH + H⁺

Thus, the two substrates of this enzyme are and NAD⁺, whereas its 3 products are , NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 3-hydroxypimeloyl-CoA:NAD⁺ oxidoreductase. This enzyme participates in .

References[]

• Harwood CS, Gibson J (1997). "Shedding light on anaerobic benzene ring degradation: a process unique to prokaryotes?". J. Bacteriol. 179 (2): 301–9. PMC 178697. PMID 8990279.