3-oxo-5beta-steroid 4-dehydrogenase
| 3-oxo-5-beta-steroid 4-dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.3.99.6 | ||||||||
| CAS no. | 9067-97-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a 3-oxo-5beta-steroid 4-dehydrogenase (EC 1.3.99.6) is an enzyme that catalyzes the chemical reaction
- a 3-oxo-5beta-steroid + acceptor a 3-oxo-Delta4-steroid + reduced acceptor
Thus, the two substrates of this enzyme are and acceptor, whereas its two products are and reduced acceptor.
This enzyme belongs to the family of oxidoreductases, to be specific, those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is 3-oxo-5beta-steroid:acceptor Delta4-oxidoreductase. This enzyme is also called 3-oxo-5beta-steroid:(acceptor) Delta4-oxidoreductase. This enzyme participates in 3 metabolic pathways: bile acid biosynthesis, , and .
References[]
- Davidson SJ, Talalay P (1966). "Purification and mechanism of action of a steroid delta-4-5-beta-dehydrogenase". J. Biol. Chem. 241 (4): 906–15. PMID 5907467.
Categories:
- EC 1.3.99
- Enzymes of unknown structure
- EC 1.3 stubs