4-chlorobenzoyl-CoA dehalogenase
4-chlorobenzoyl-CoA dehalogenase | |||||||||
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Identifiers | |||||||||
EC no. | 3.8.1.7 | ||||||||
CAS no. | 141583-18-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a 4-chlorobenzoyl-CoA dehalogenase (EC 3.8.1.7) is an enzyme that catalyzes the chemical reaction
- 4-chlorobenzoyl-CoA + H2O 4-hydroxybenzoyl CoA + chloride
Thus, the two substrates of this enzyme are and H2O, whereas its two products are and chloride.
This enzyme belongs to the family of hydrolases, specifically those acting on halide bonds in carbon-halide compounds. The systematic name of this enzyme class is 4-chlorobenzoyl CoA chlorohydrolase. This enzyme participates in .
References[]
- Chang KH, Liang PH, Beck W, Scholten JD, Dunaway-Mariano D (1992). "Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3". Biochemistry. 31 (24): 5605–10. doi:10.1021/bi00139a025. PMID 1610806.
- Crooks GP, Copley SD (1994). "Purification and characterization of 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain 4-CB1". Biochemistry. 33 (38): 11645–9. doi:10.1021/bi00204a028. PMID 7918379.
Categories:
- EC 3.8.1
- Enzymes of unknown structure
- Hydrolase stubs