6-hydroxymellein O-methyltransferase

In enzymology, a 6-hydroxymellein O-methyltransferase (EC 2.1.1.108) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 6-hydroxymellein ${\displaystyle \rightleftharpoons }$ S-adenosyl-L-homocysteine + 6-methoxymellein

Thus, the two substrates of this enzyme are S-adenosyl methionine and 6-hydroxymellein, whereas its two products are S-adenosylhomocysteine and 6-methoxymellein.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:6-hydroxymellein 6-O-methyltransferase. This enzyme is also called 6-hydroxymellein methyltransferase.

References[]

• Kurosaki F, Nishi A (1988). "A methyltransferase for synthesis of the phytoalexin 6-methoxymellein in carrot cells". FEBS Lett. 227 (2): 183–186. doi:10.1016/0014-5793(88)80894-9.