Biliverdin reductase A
biliverdin reductase A | |||||||||
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![]() Biliverdin reductase A dimer, Human | |||||||||
Identifiers | |||||||||
EC no. | 1.3.1.24 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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BLVRA | |||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||
Aliases | BLVRA, BLVR, BVR, BVRA, biliverdin reductase A | ||||||||||||||||||||||||
External IDs | OMIM: 109750 MGI: 88170 HomoloGene: 572 GeneCards: BLVRA | ||||||||||||||||||||||||
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Orthologs | |||||||||||||||||||||||||
Species | Human | Mouse | |||||||||||||||||||||||
Entrez | |||||||||||||||||||||||||
Ensembl | |||||||||||||||||||||||||
UniProt | |||||||||||||||||||||||||
RefSeq (mRNA) | |||||||||||||||||||||||||
RefSeq (protein) | |||||||||||||||||||||||||
Location (UCSC) | Chr 7: 43.76 – 43.81 Mb | Chr 2: 127.07 – 127.1 Mb | |||||||||||||||||||||||
PubMed search | [3] | [4] | |||||||||||||||||||||||
Wikidata | |||||||||||||||||||||||||
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Biliverdin reductase A is a protein that in humans is encoded by the BLVRA gene.[5]
Function[]
The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH.[5]
Clinical significance[]
Mutations in this gene are associated with hyperbiliverdinemia.[5]
References[]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000106605 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001999 - Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b c "Entrez Gene: Biliverdin reductase A".
External links[]
- Human BLVRA genome location and BLVRA gene details page in the UCSC Genome Browser.
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Biliverdin reductase A
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Categories:
- Genes on human chromosome 7
- EC 1.3.1
- Human chromosome 7 gene stubs