Cantuzumab ravtansine
Monoclonal antibody | |
---|---|
Type | Whole antibody |
Source | Humanized (from mouse) |
Target | MUC1 |
Clinical data | |
ATC code |
|
Identifiers | |
CAS Number | |
ChemSpider |
|
UNII | |
KEGG | |
(what is this?) |
Cantuzumab ravtansine (huC242-SPDB-DM4) is an antibody-drug conjugate designed for the treatment of cancers. The humanized monoclonal antibody cantuzumab (huC242) is linked to a cytotoxic agent, ravtansine (DM4).[1] It uses a more hindered disulfide linkage than cantuzumab mertansine.[2]
See also[]
- Cantuzumab mertansine
- ImmunoGen Inc, developer of DM4 based drugs
References[]
- ^ World Health Organization (2011). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 105" (PDF). WHO Drug Information. 25 (2). Archived from the original (PDF) on April 1, 2012.
- ^ Antibody-Drug Conjugates and Immunotoxins: From Pre-Clinical Development to ...
Categories:
- Drugs not assigned an ATC code
- Immunology
- Monoclonal antibodies
- Monoclonal antibody stubs