DDT-dehydrochlorinase
DDT-dehydrochlorinase | |||||||||
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Identifiers | |||||||||
EC no. | 4.5.1.1 | ||||||||
CAS no. | 9031-20-3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a DDT-dehydrochlorinase (EC 4.5.1.1) is an enzyme that catalyzes the chemical reaction
1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride
Hence, this enzyme has one substrate, 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane, and two products, and chloride.
This enzyme belongs to the family of lyases, specifically the class of carbon-halide lyases. The systematic name of this enzyme class is 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase [1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene-forming]. Other names in common use include DDT-ase, 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase, dehydrohalogenase, and DDTase. This enzyme participates in 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) and .
References[]
- LIPKE H, KEARNS CW (1959). "DDT dehydrochlorinase. I. Isolation, chemical properties, and spectrophotometric assay". J. Biol. Chem. 234 (8): 2123–8. PMID 13673024.
- LIPKE H, KEARNS CW (1959). "DDT dehydrochlorinase. II. Substrate and cofactor specificity". J. Biol. Chem. 234 (8): 2129–32. PMID 13673025.
- Moorefield HH (1956). "Purification of DDT-dehydrochlorinase from resistant houseflies". Contr. Boyce Thompson Inst. 18: 303–310.
Categories:
- EC 4.5.1
- Enzymes of unknown structure
- Lyase stubs