Demethylsterigmatocystin 6-O-methyltransferase

In enzymology, a demethylsterigmatocystin 6-O-methyltransferase (EC 2.1.1.109) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 6-demethylsterigmatocystin ${\displaystyle \rightleftharpoons }$ S-adenosyl-L-homocysteine + sterigmatocystin

Thus, the two substrates of this enzyme are S-adenosyl methionine and , whereas its two products are S-adenosylhomocysteine and sterigmatocystin.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:6-demethylsterigmatocystin 6-O-methyltransferase. Other names in common use include demethylsterigmatocystin methyltransferase, and O-methyltransferase I.

References[]

• Yabe K, Ando Y, Hashimoto J, Hamasaki T (1989). "Two distinct O-methyltransferases in aflatoxin biosynthesis". Appl. Environ. Microbiol. 55 (9): 2172–7. PMC 203052. PMID 2802602.