From Wikipedia, the free encyclopedia
Deoxyschizandrin
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Names
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Preferred IUPAC name
(6R,7S)-1,2,3,10,11,12-Hexamethoxy-6,7-dimethyl-5,6,7,8-tetrahydrodibenzo[a,c][8]annulene
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Other names
Schizandrin A; Schisandrin A; Dimethylgomisin J
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Identifiers
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- 61281-38-7 Y
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3D model (JSmol)
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ChEBI
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ChEMBL
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ChemSpider
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KEGG
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UNII
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InChI=1S/C24H32O6/c1-13-9-15-11-17(25-3)21(27-5)23(29-7)19(15)20-16(10-14(13)2)12-18(26-4)22(28-6)24(20)30-8/h11-14H,9-10H2,1-8H3/t13-,14+ Key: JEJFTTRHGBKKEI-OKILXGFUSA-N
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C[C@@H]1CC2=CC(=C(C(=C2C3=C(C(=C(C=C3C[C@@H]1C)OC)OC)OC)OC)OC)OC
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Properties
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Chemical formula
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C24H32O6
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Molar mass
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416.514 g·mol−1
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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Chemical compound
Deoxyschizandrin is a bio-active isolate of Schisandra chinensis.[1]
Deoxyschizandrin has been found to act as an agonist of the adiponectin receptor 2 (AdipoR2).[2]
References[]
- ^ Chang, R; Li, Y; Yang, X; Yue, Y; Dou, L; Wang, Y; Zhang, W; Li, X (2013). Ma, Xin-Liang (ed.). "Protective role of deoxyschizandrin and schisantherin a against myocardial ischemia-reperfusion injury in rats". PLOS ONE. 8 (4): e61590. Bibcode:2013PLoSO...861590C. doi:10.1371/journal.pone.0061590. PMC 3631228. PMID 23620773.
- ^ Sun Y, Zang Z, Zhong L, Wu M, Su Q, Gao X, Zan W, Lin D, Zhao Y, Zhang Z (2013). "Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay". PLOS ONE. 8 (5): e63354. Bibcode:2013PLoSO...863354S. doi:10.1371/journal.pone.0063354. PMC 3653934. PMID 23691032.
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Adiponectin | |
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Angiotensin | |
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Bradykinin | |
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CGRP |
- Agonists: Amylin
- CGRP
- Pramlintide
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Cholecystokinin | |
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CRH | |
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Cytokine | See here instead. |
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Endothelin | |
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Galanin | |
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Ghrelin/GHS | |
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GH | |
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GHRH | |
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GLP | |
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Glucagon | |
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GnRH | |
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Gonadotropin | |
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Growth factor | See here instead. |
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Insulin |
- Antibodies: (against IGF-1 and IGF-2)
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Kisspeptin | |
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Leptin |
- Agonists: Leptin
- Metreleptin
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MCH | |
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Melanocortin | |
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Neuropeptide FF | |
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Neuropeptide S | |
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Neuropeptide Y | Y1 |
- Agonists: Neuropeptide Y
- Peptide YY
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Y2 |
- Agonists:
- Neuropeptide Y
- Peptide YY
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Y4 |
- Agonists:
- Neuropeptide Y
- Pancreatic polypeptide
- Peptide YY
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Y5 |
- Agonists:
- Neuropeptide Y
- Peptide YY
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Neurotensin | |
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Opioid | See here instead. |
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Orexin | |
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Oxytocin | |
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Prolactin | |
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PTH | |
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Relaxin | |
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Somatostatin | |
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Tachykinin | |
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TRH | |
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TSH |
- Agonists: Thyrotropin alfa
- TSH (thyrotropin)
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Vasopressin | |
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VIP/PACAP | |
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Others |
- Endogenous: Adrenomedullin
- Apelin
- Asprosin
- Bombesin
- Calcitonin
- Carnosine
- CART
- CLIP
- DSIP
- Enteroglucagon
- Formyl peptide
- GALP
- GIP
- GRP
- Integrin ligands (collagens, fibrinogen, fibronectin, laminins, ICAM-1, ICAM-2, osteopontin, VCAM-1, vitronectin)
- Kininogens
- Motilin
- Natriuretic peptides (ANP, BNP, CNP, urodilatin)
- Nesfatin-1
- Neuromedin B
- Neuromedin N
- Neuromedin S
- Neuromedin U
- Obestatin
- Osteocalcin
- Resistin
- Secretin
- Thymopoietin
- Thymosins
- Thymulin
- Urotensin-II
- VGF
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- See also
- Receptor/signaling modulators
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Categories:
- Adiponectin receptor agonists
- Phytochemicals
- Organic compound stubs
Hidden categories:
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