From Wikipedia, the free encyclopedia
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 is a protein that in humans is encoded by the GNG12 gene .[5] [6]
References [ ]
^ a b c GRCh38: Ensembl release 89: ENSG00000172380 - Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036402 - Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Hurowitz EH, Melnyk JM, Chen YJ, Kouros-Mehr H, Simon MI, Shizuya H (Sep 2000). "Genomic characterization of the human heterotrimeric G protein alpha, beta, and gamma subunit genes" . DNA Res . 7 (2): 111–20. doi :10.1093/dnares/7.2.111 PMID 10819326 . ^ "Entrez Gene: GNG12 guanine nucleotide binding protein (G protein), gamma 12" .
Further reading [ ]
Morishita R, Nakayama H, Isobe T, et al. (1996). "Primary structure of a gamma subunit of G protein, gamma 12, and its phosphorylation by protein kinase C." J. Biol. Chem . 270 (49): 29469–75. doi :10.1074/jbc.270.49.29469 PMID 7493986 . Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene . 138 (1–2): 171–4. doi :10.1016/0378-1119(94)90802-8 . PMID 8125298 . Morishita R, Saga S, Kawamura N, et al. (1997). "Differential localization of the gamma 3 and gamma 12 subunits of G proteins in the mammalian brain" . J. Neurochem . 68 (2): 820–7. doi :10.1046/j.1471-4159.1997.68020820.x PMID 9003074 . Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene . 200 (1–2): 149–56. doi :10.1016/S0378-1119(97)00411-3 . PMID 9373149 . Asano T, Morishita R, Ueda H, Kato K (1999). "Selective association of G protein beta(4) with gamma(5) and gamma(12) subunits in bovine tissues" . J. Biol. Chem . 274 (30): 21425–9. doi :10.1074/jbc.274.30.21425 PMID 10409705 . Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning" . Proc. Natl. Acad. Sci. U.S.A . 97 (17): 9543–8. Bibcode :2000PNAS...97.9543H . doi :10.1073/pnas.160270997 PMC 16901 PMID 10931946 . Cook LA, Schey KL, Cleator JH, et al. (2002). "Identification of a region in G protein gamma subunits conserved across species but hypervariable among subunit isoforms" . Protein Sci . 10 (12): 2548–55. doi :10.1110/ps.ps.26401 . PMC 2374038 PMID 11714923 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Cuello F, Schulze RA, Heemeyer F, et al. (2003). "Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta" . J. Biol. Chem . 278 (9): 7220–6. doi :10.1074/jbc.M210304200 PMID 12486123 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol . 6 (2): 97–105. doi :10.1038/ncb1086 . PMID 14743216 . S2CID 11683986 . Kato C, Mizutani T, Tamaki H, et al. (2004). "Characterization of heterotrimeric G protein complexes in rice plasma membrane". Plant J . 38 (2): 320–31. doi :10.1111/j.1365-313X.2004.02046.x . PMID 15078334 . Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions" . Genome Res . 14 (9): 1711–8. doi :10.1101/gr.2435604 . PMC 515316 PMID 15342556 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 PMID 17081983 . S2CID 7827573 .
Intracellular signaling peptides and proteins
MAP Calcium G protein
Cyclin Lipid Other protein kinase
Other protein phosphatase
Apoptosis
see apoptosis signaling pathway GTP-binding protein regulators
see GTP-binding protein regulators Other see also deficiencies of intracellular signaling peptides and proteins
Categories :
Genes on human chromosome 1 Human chromosome 1 gene stubs
