Hydrogen:quinone oxidoreductase

In enzymology, a hydrogen:quinone oxidoreductase (EC 1.12.5.1) is an enzyme that catalyzes the chemical reaction

H₂ + quinone ${\displaystyle \rightleftharpoons }$ quinol

Thus, the two substrates of this enzyme are H₂ and quinone, whereas its product is quinol. The quinone can be menaquinone, ubiquinone, or .

This enzyme belongs to the family of oxidoreductases, specifically those acting on hydrogen as donor with a quinone or similar compound as acceptor. The systematic name of this enzyme class is hydrogen:quinone oxidoreductase. Other names in common use include hydrogen-ubiquinone oxidoreductase, hydrogen:menaquinone oxidoreductase, membrane-bound hydrogenase, and quinone-reactive Ni/Fe-hydrogenase.

References[]

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• Kodama T (1991). "Methionaquinone is a direct natural electron-acceptor for the membrane-bound hydrogenase in Hydrogenobacter thermophilus strain TK-6". Agric. Biol. Chem. 55: 3011–3016. doi:10.1271/bbb1961.55.3011.
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• Frielingsdorf, Stefan; Schubert, Torsten; Pohlmann, Anne; Lenz, Oliver; Friedrich, Bärbel (2011). "A Trimeric Supercomplex of the Oxygen-Tolerant Membrane-Bound [NiFe]-Hydrogenase fromRalstonia eutrophaH16". Biochemistry. 50 (50): 10836–10843. doi:10.1021/bi201594m. ISSN 0006-2960.
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