Isobutyraldoxime O-methyltransferase

In enzymology, an isobutyraldoxime O-methyltransferase (EC 2.1.1.91) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 2-methylpropanal oxime ${\displaystyle \rightleftharpoons }$ S-adenosyl-L-homocysteine + 2-methylpropanal O-methyloxime

Thus, the two substrates of this enzyme are S-adenosyl methionine and , whereas its two products are S-adenosylhomocysteine and .

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:2-methylpropanal-oxime O-methyltransferase. Other names in common use include aldoxime methyltransferase, S-adenosylmethionine:aldoxime O-methyltransferase, and aldoxime O-methyltransferase.

References[]

• Harper DB, Kennedy JT (1985). "Purification and properties of S-adenosylmethionine: aldoxime O-methyltransferase from Pseudomonas sp. N.C.I.B. 11652". Biochem. J. 226 (1): 147–53. PMC 1144687. PMID 3977861.