Isoflavone-7-O-beta-glucoside 6"-O-malonyltransferase

In enzymology, an isoflavone-7-O-beta-glucoside 6"-O-malonyltransferase (EC 2.3.1.115) is an enzyme that catalyzes the chemical reaction

malonyl-CoA + biochanin A 7-O-beta-D-glucoside ${\displaystyle \rightleftharpoons }$ CoA + biochanin A 7-O-(6-O-malonyl-beta-D-glucoside)

Thus, the two substrates of this enzyme are malonyl-CoA and biochanin A 7-O-beta-D-glucoside, whereas its two products are CoA and biochanin A 7-O-(6-O-malonyl-beta-D-glucoside).

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:isoflavone-7-O-beta-D-glucoside 6"-O-malonyltransferase. Other names in common use include flavone/flavonol 7-O-beta-D-glucoside malonyltransferase, flavone (flavonol) 7-O-glycoside malonyltransferase, malonyl-CoA:flavone/flavonol 7-O-glucoside malonyltransferase, MAT-7, malonyl-coenzyme A:isoflavone 7-O-glucoside-6"-malonyltransferase, and malonyl-coenzyme A:flavone/flavonol-7-O-glycoside malonyltransferase. This enzyme participates in flavonoid biosynthesis and isoflavonoid biosynthesis.

References[]

• Koester J, Bussmann R, Barz W (1984). "Malonyl-coenzyme A:isoflavone 7-O-glucoside-6"-O-malonyltransferase from roots of chick pea (Cicer arietinum L.)". Arch. Biochem. Biophys. 234 (2): 513–21. doi:10.1016/0003-9861(84)90298-4. PMID 6497385.
• Matern U, Feser C, Hammer D (1983). "Further characterization and regulation of malonyl-coenzyme A: flavonoid glucoside malonyltransferases from parsley cell suspension cultures". Arch. Biochem. Biophys. 226 (1): 206–17. doi:10.1016/0003-9861(83)90286-2. PMID 6639051.