KRT78

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KRT78
Identifiers
AliasesKRT78, CK-78, K5B, K78, Kb40, keratin 78
External IDsOMIM: 611159 MGI: 1917529 HomoloGene: 65261 GeneCards: KRT78
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001300814
NM_173352

NM_212487

RefSeq (protein)

NP_001287743
NP_775487

n/a

Location (UCSC)Chr 12: 52.84 – 52.85 MbChr 15: 101.85 – 101.86 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Keratin, type II cytoskeletal 78 is a protein that in humans is encoded by the KRT78 gene.[5][6]

This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.[6]

References[]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000170423 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050463 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
  6. ^ a b "Entrez Gene: KRT78 keratin 78".

Further reading[]


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