List of restriction enzyme cutting sites: Bsp–Bss

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Legend of nucleobases
Code Nucleotide represented
A Adenine (A)
C Cytosine (C)
G Guanine (G)
T Thymine (T)
N A, C, G or T
M A or C
R A or G
W A or T
Y C or T
S C or G
K G or T
H A, C or T
B C, G or T
V A, C or G
D A, G or T

This article contains a list of the most studied restriction enzymes whose names start with Bsp to Bss inclusive. It contains approximately 180 enzymes.

The following information is given:

  • Enzyme: Accepted name of the molecule, according to the internationally adopted nomenclature[1][2], and bibliographical references. (Further reading: see the section "Nomenclature" in the article "Restriction enzyme".)
  • PDB code: Code used to identify the structure of a protein in the PDB database of protein structures. The 3D atomic structure of a protein provides highly valuable information to understand the intimate details of its mechanism of action[3][4].
  • Source: Organism that naturally produces the enzyme.
  • Recognition sequence: Sequence of DNA recognized by the enzyme and to which it specifically binds.
  • Cut: Cutting site and DNA products of the cut. The recognition sequence and the cutting site usually match, but sometimes the cutting site can be dozens of nucleotides away from the recognition site[5][6].
  • Isoschizomers and neoschizomers: An isoschizomer is an enzyme that recognizes the same sequence as another. A neoschizomer is a special type of isoschizomer that recognizes the same sequence as another, but cuts in a different manner. A maximum number of 8-10 most common isoschizomers are indicated for every enzyme but there may be many more. Neoschizomers are shown in bold and green color font (e.g.: BamHI). When "None on date" is indicated, that means that there were no registered isoschizomers in the databases on that date with a clearly defined cutting site. Isoschizomers indicated in white font and grey background correspond to enzymes not listed in the current lists:
as in this not listed enzyme:  EcoR70I 


Whole list navigation[]

Restriction enzymes[]

Bsp[]

Enzyme PDB code Source Recognition sequence Cut Isoschizomers
Bacillus sp. RFL6 5' GCNGC
3' CGNCG
5' ---GC   NGC--- 3'
3' ---CGN   CG--- 5'
Bacillus sp. 13 5' TCCGGA
3' AGGCCT
5' ---T   CCGGA--- 3'
3' ---AGGCC   T--- 5'
AccIII, BbvAIII, BlfI, BsiMI, BspMII, Bsu23I, Kpn2I, PinBII
Bacillus sp. 19 5' CCATGG
3' GGTACC
5' ---C   CATGG--- 3'
3' ---GGTAC   C--- 5'
Bacillus sp. 24 5' GACN6TGG
3' CTGN6ACC
5' ---GACN6TGGN6NNNNNN   --- 3'
3' ---CTGN6ACCN6N   NNNNN--- 5'
Bacillus sp. RFL50 5' CGCG
3' GCGC
5' ---CG   CG--- 3'
3' ---GC   GC--- 5'
BceBI, Bsh1236I, BstFNI, BstUI, Bsu1532I, FalII, FnuDII, MvnI, ThaI
Bacillus sphaericus 63 5' CTGCAG
3' GACGTC
5' ---CTGCA   G--- 3'
3' ---G   ACGTC--- 5'
AjoI, Asp713I, BloHII, MhaAI, Pfl21I, PstI, SalPI, SflI, Sst12I, YenI
Bacillus sphaericus 67 5' GATC
3' CTAG
5' ---   GATC--- 3'
3' ---CTAG   --- 5'
AspMDI, Bsp143I, BspJI, BtkII, DpnII, LlaAI, NlaII, SsiBI
Bacillus sp. RFL68 5' TCGCGA
3' AGCGCT
5' ---TCG   CGA--- 3'
3' ---AGC   GCT--- 5'
NruI
Bacillus sp. RFL98 5' GGATCC
3' CCTAGG
5' ---G   GATCC--- 3'
3' ---CCTAG   G--- 5'
AccEBI, AliI, BamHI, BnaI, BstI, CelI, OkrAI, NspSAIV, Pfl8I, SurI
Bacillus sphaericus 105 5' GATC
3' CTAG
5' ---   GATC--- 3'
3' ---CTAG   --- 5'
Bfi57I, Bsp143I, BspJI, BtkII, DpnII, LlaAI, NlaII, SsiBI
Bacillus sphaericus 106 5' ATCGAT
3' TAGCTA
5' ---AT   CGAT--- 3'
3' ---TAGC   TA--- 5'
BbvAII, Bci29I, BciBI, BcmI, BspOVII, BstNZ169I, Rme21I
Bacillus sp. RFL119 5' TTCGAA
3' AAGCTT
5' ---TT   CGAA--- 3'
3' ---AAGC   TT--- 5'
AcpI, Bim19I, Bpu14I, BspT104I, Csp45I, FspII, NspV, SspRFI
Bacillus sp. RFL120 5' GGGCCC
3' CCCGGG
5' ---G   GGCCC--- 3'
3' ---CCCGG   G--- 5'
ApaI, PpeI, PspOMI
Bacillus sp. 123 5' CGCG
3' GCGC
5' ---CG   CG--- 3'
3' ---GC   GC--- 5'
BceBI, Bsh1236I, BstFNI, BstUI, BtkI, Csp68KVI, FnuDII, MvnI, ThaI
Bacillus sp. RFL143 5' GATC
3' CTAG
5' ---   GATC--- 3'
3' ---CTAG   --- 5'
Bce243I, Bsp105I, BspFI, BstKTI, CpfI, HacI, NdeII, Sth368I, Sau3AI
Bacillus sp. RFL143 5' RGCGCY
3' YCGCGR
5' ---RGCGC   Y--- 3'
3' ---Y   CGCGR--- 5'
AccB2I,  BfoI,  Bme142I, BstH2I,
HaeII, LpnI
Bacillus sphaericus 211 5' GGCC
3' CCGG
5' ---GG   CC--- 3'
3' ---CC   GG--- 5'
Bacillus sp. 423 5' GCAGC
3' CGTCG
5' ---GCAGCN7N   NNNN--- 3'
3' ---CGTCGN7NNNNN   --- 5'
AlwXI, BbvI, BseKI, BseXI, Bst12I, Bst71I, BstV1I
Bacillus sp. 519 5' GRGCYC
3' CYCGRG
5' ---GRGCY   C--- 3'
3' ---C   YCGRG--- 5'
Bacillus sphaericus 5' GDGCHC
3' CHCGDG
5' ---GDGCH   C--- 3'
3' ---C   HCGDG--- 5'
AocII, BmyI, BsoCI, Bsp1286I, BspLS2I, NspII, SduI
Bacillus stearothermophilus RFL1407 5' TGTACA
3' ACATGT
5' ---T   GTACA--- 3'
3' ---ACATG   T--- 5'
AauI,  BsmRI,  BsrGI, BstAUI,
Ssp4800I, SspBI
Bacillus sp. 1720 5' GCTNAGC
3' CGANTCG
5' ---GC   TNAGC--- 3'
3' ---CGANT   CG--- 5'
Bacillus sphaericus 1894 5' GGNCC
3' CCNGG
5' ---G   GNCC--- 3'
3' ---CCNG   G--- 5'
AspS9I, Bac36I, BavBII, BshKI, BspBII, CcuI, MaeK81II, Pde12I
Bacillus sphaericus 2095 5' GATC
3' CTAG
5' ---   GATC--- 3'
3' ---CTAG   --- 5'
Bfi57I, Bsp143I, BspKT6I, BtkII, DpnII, LlaAI, NlaII, SsiBI
Bacillus sp. 4009 5' GGATCC
3' CCTAGG
5' ---G   GATCC--- 3'
3' ---CCTAG   G--- 5'
AccEBI, AliI, ApaCI, BamHI, BstI, CelI, OkrAI, Pfl8I, RspLKII, SurI
Bacillus sphaericus JL4B 5' GATC
3' CTAG
5' ---   GATC--- 3'
3' ---CTAG   --- 5'
Bfi57I, Bsp2095I, BspKT6I, BtkII, DpnII, LlaAI, NlaII, SsiBI
Bacillus sp. A2 5' CCTAGG
3' GGATCC
5' ---C   CTAGG--- 3'
3' ---GGATC   C--- 5'
AspA2I, AvrII, AvrBII, BlnI, XmaJI
Bacillus sp. 153A 5' CAGCTG
3' GTCGAC
5' ---CAG   CTG--- 3'
3' ---GTC   GAC--- 5'
Bacillus sp. AA 5' CTCGAG
3' GAGCTC
5' ---C   TCGAG--- 3'
3' ---GAGCT   C--- 5'
AbrI, BluI, BstVI, PanI, SauLPII, SciI, SlaI, StrI, TliI
Bacillus sp. AA 5' TCTAGA
3' AGATCT
5' ---T   CTAGA--- 3'
3' ---AGATC   T--- 5'
Bacillus sp. AA 5' GGATCC
3' CCTAGG
5' ---G   GATCC--- 3'
3' ---CCTAG   G--- 5'
AccEBI, AliI, ApaCI, AsiI, BamHI, Bce751I, Pfl8I, RspLKII, SolI
Bacillus sp. AN 5' GGCC
3' CCGG
5' ---GG   CC--- 3'
3' ---CC   GG--- 5'
Bacillus sphaericus JL14 5' CTGCAG
3' GACGTC
5' ---CTGCA   G--- 3'
3' ---G   ACGTC--- 5'
AjoI, ApiI, Asp713I, BloHII, CfrA4I, Pfl21I, PstI, SalPI, Sst12I, YenI
Bacillus sphaericus JL14 5' GGNCC
3' CCNGG
5' ---G   GNCC--- 3'
3' ---CCNG   G--- 5'
AsuI, Bac36I, BavBII, BshKI, BspF4I, CcuI, MaeK81II, PspPI
Bacillus sp. 5' GGCC
3' CCGG
5' ---GG   CC--- 3'
3' ---CC   GG--- 5'
Bacillus sp. BS31 5' GAAGAC
3' CTTCTG
5' ---GAAGACNN   NNNN--- 3'
3' ---CTTCTGNNNNNN   --- 5'
Bacillus sp. C1 5' CGATCG
3' GCTAGC
5' ---CGAT   CG--- 3'
3' ---GC   TAGC--- 5'
Afa16RI, Afa22MI, EagBI, ErhB9I, NblI, Psu161I, RshI, XorII
Bacillus sp. 1310 5' CTCAG
3' GAGTC
5' ---CTCAGN6NNN   --- 3'
3' ---GAGTCN6N   NN--- 5'
Bacillus sp. 5' ATCGAT
3' TAGCTA
5' ---AT   CGAT--- 3'
3' ---TAGC   TA--- 5'
AagI, BanIII, BavCI, Bsa29I, BseCI, Bsu15I, BsuTUI, ClaI, ZhoI
[7][8] 2P14 Bacillus sp. D6 5' GACTC
3' CTGAG
5' ---GACTCNNNN   NN--- 3'
3' ---CTGAGNNNNNN   --- 5'
Bacillus sp. 5' TCCGGA
3' AGGCCT
5' ---T   CCGGA--- 3'
3' ---AGGCC   T--- 5'
AccIII, BlfI, BsiMI, Bsp13I, BspMII, CauB3I, MroI, PinBII
Bacillus sp. 5' GATC
3' CTAG
5' ---   GATC--- 3'
3' ---CTAG   --- 5'
Bfi57I, Bsp2095I, BspKT6I, BtkII, DpnII, LlaAI, NlaII, SsiBI
Bacillus sp. F4 5' GGNCC
3' CCNGG
5' ---G   GNCC--- 3'
3' ---CCNG   G--- 5'
AsuI, Bac36I, BavBII, BsiZI, BspBII, CcuI, MaeK81II, PspPI
Bacillus sp. H3 5' TCATGA
3' AGTACT
5' ---T   CATGA--- 3'
3' ---AGTAC   T--- 5'
Bacillus sp. IS4 5' GAAGAC
3' CTTCTG
5' ---GAAGACNN   NNNN--- 3'
3' ---CTTCTGNNNNNN   --- 5'
Bacillus sp. 5' GATC
3' CTAG
5' ---   GATC--- 3'
3' ---CTAG   --- 5'
BfuCI, Bsp2095I, BspKT6I, BtkII, DpnII, LlaAI, NmeCI, SsiAI
Bacillus sp. 5' ATCGAT
3' TAGCTA
5' ---AT   CGAT--- 3'
3' ---TAGC   TA--- 5'
Bsa29I, BseCI, Bsp106I, BspDI, BspOVII, BspXI, BspZEI
Bacillus sp. K 5' GGCC
3' CCGG
5' ---GG   CC--- 3'
3' ---CC   GG--- 5'
Bacillus sp. 5' CTGAAG
3' GACTTC
5' ---CTGAAGN12NNNN   --- 3'
3' ---GACTTCN12NN   NN--- 5'
Bacillus sp. KT6 5' GATC
3' CTAG
5' ---GAT   C--- 3'
3' ---C   TAG--- 5'
BfuCI, Bsp2095I, Bst19II, BstKTI, DpnII, LlaAI, NmeCI, SsiAI
Bacillus sp. KT8 5' AAGCTT
3' TTCGAA
5' ---A   AGCTT--- 3'
3' ---TTCGA   A--- 5'
Bacillus sp. RJ3-212 5' GGNNCC
3' CCNNGG
5' ---GGN   NCC--- 3'
3' ---CCN   NGG--- 5'
AspNI, BscBI,  BmiI,  NlaIV,
PspN4I
Bacillus sp. LA 5' GCGC
3' CGCG
5' ---GCG   C--- 3'
3' ---C   GCG--- 5'
AspLEI, BstHHI, CfoI, FnuDIII, HhaI, Hin6I, HinP1I, HsoI, HspAI, SciNI
Bacillus sp. LA 5' TTCGAA
3' AAGCTT
5' ---TT   CGAA--- 3'
3' ---AAGC   TT--- 5'
Bacillus sp. LA 5' AAGCTT
3' TTCGAA
5' ---A   AGCTT--- 3'
3' ---TTCGA   A--- 5'
Bacillus sp. LS2 5' GDGCHC
3' CHCGDG
5' ---GDGCH   C--- 3'
3' ---C   HCGDG--- 5'
AocII, BmyI, BsoCI, BspLS2I, MhlI, NspII, SduI
Bacillus sp. LU4 5' CYCGRG
3' GRGCYC
5' ---C   YCGRG--- 3'
3' ---GRGCY   C--- 5'
Ama87I, AvaI, Bse15I, BsoBI, BstSI, NspIII, NspSAI, OfoI
Bacillus sp. LU11 5' ACATGT
3' TGTACA
5' ---A   CATGT--- 3'
3' ---TGTAC   A--- 5'
Bacillus sp. LU11 5' GGGAC
3' CCCTG
5' ---GGGACN8NN   NNNN--- 3'
3' ---CCCTGN8NNNNNN   --- 5'
Bacillus sp. M 5' ACCTGC
3' TGGACG
5' ---ACCTGCNNNN   NNNN--- 3'
3' ---TGGACGNNNNNNNN   --- 5'
Acc36I, BfuAI, BveI
Bacillus sp. M 5' TCCGGA
3' AGGCCT
5' ---T   CCGGA--- 3'
3' ---AGGCC   T--- 5'
AccIII, BbvAIII, BlfI, BsiMI, BspEI, Bsu23I, CauB3I, MroI
Bacillus sp. M39 5' CAGCTG
3' GTCGAC
5' ---CAG   CTG--- 3'
3' ---GTC   GAC--- 5'
Bacillus sp. M90 5' GTATAC
3' CATATG
5' ---GTA   TAC--- 3'
3' ---CAT   ATG--- 5'
Bacillus stearothermophilus MA 5' CTGCAG
3' GACGTC
5' ---CTGCA   G--- 3'
3' ---G   ACGTC--- 5'
AjoI, Asp713I, BloHII, PaePI, Psp23I, PstI, SalPI, Sst12I, YenI
Bacillus sp. MKI 5' GTCGAC
3' CAGCTG
5' ---G   TCGAC--- 3'
3' ---CAGCT   G--- 5'
Bacillus sp. N 5' CCWGG
3' GGWCC
5' ---CC   WGG--- 3'
3' ---GGW   CC--- 5'
AglI, BseBI, Bse17I, Bst2I, CbrI, CthII, EcoRII, MvaI, SspAI, TaqXI
Bacillus sp. O-4 5' CAGCTG
3' GTCGAC
5' ---CAG   CTG--- 3'
3' ---GTC   GAC--- 5'
Bacillus sp. OV 5' GACN5GTC
3' CTGN5CAG
5' ---GACNNN   NNGTC--- 3'
3' ---CTGNN   NNNCAG--- 5'
AhdI, AspEI,  BmeRI,  DriI,
Eam1105I, EclHKI, NruGI
Bacillus sp. OV 5' ATCGAT
3' TAGCTA
5' ---AT   CGAT--- 3'
3' ---TAGC   TA--- 5'
BanIII, BavCI, BciBI, BcmI, Bli86I, BliRI, BspJII, BstNZ169I, SpmI
Bacillus sp. d 1-34 5' GGATC
3' CCTAG
5' ---GGATCNNNN   N--- 3'
3' ---CCTAGNNNNN   --- 5'
AclWI, AlwI, BinI,  BsrWI, 
BstH9I,  Bst31TI, Bth617I,  EacI
Bacillus sphaericus R 5' GGCC
3' CCGG
5' ---GG   CC--- 3'
3' ---CC   GG--- 5'
Bacillus sp. R7 5' CCTNAGG
3' GGANTCC
5' ---CC   TNAGG--- 3'
3' ---GGANT   CC--- 5'
AocI, AxyI, Bse21I, Bsu36I, Eco81I, MstII, SauI, SshAI
Bacillus sp. ST5 5' GCATC
3' CGTAG
5' ---GCATCN4N   NNNN--- 3'
3' ---CGTAGN4NNNNN   --- 5'
Bacillus sp. RFL1265 5' CTTAAG
3' GAATTC
5' ---C   TTAAG--- 3'
3' ---GAATT   C--- 5'
AflII
Bacillus sp. T104 5' TTCGAA
3' AAGCTT
5' ---TT   CGAA--- 3'
3' ---AAGC   TT--- 5'
AcpI, Bim19I, Bpu14I, BstBI, Csp45I, LspI, NspV, SspRFI
Bacillus sp. T107 5' GGYRCC
3' CCRYGG
5' ---G   GYRCC--- 3'
3' ---CCRYG   G--- 5'
AccB1I, BanI, BbvBI, Eco64I, HgiCI, HgiHI, MspB4I, PfaAI
Bacillus sp. TN 5' GGTCTC
3' CCAGAG
5' ---GGTCTCN   NNNN--- 3'
3' ---CCAGAGNNNNN   --- 5'
Bacillus sp. TS514 5' GAAGAC
3' CTTCTG
5' ---GAAGACNN   NNNN--- 3'
3' ---CTTCTGNNNNNN   --- 5'
Bacillus sp. 3456 5' GCN7GC
3' CGN7CG
5' ---GCNNNNN   NNGC--- 3'
3' ---CGNN   NNNNNCG--- 5'
Bacillus sphaericus X 5' ATCGAT
3' TAGCTA
5' ---AT   CGAT--- 3'
3' ---TAGC   TA--- 5'
BliAI, BliRI, BscI, Bst28I, Bsu15I, LcaI, PgaI, Ssp27144I, ZhoI
Bacillus sphaericus X 5' TGATCA
3' ACTAGT
5' ---T   GATCA--- 3'
3' ---ACTAG   T--- 5'
AbaI, BclI, BsiQI,
BstT7I, FbaI, Ksp22I,  ParI 
Bacillus sp. ZE 5' ATCGAT
3' TAGCTA
5' ---AT   CGAT--- 3'
3' ---TAGC   TA--- 5'
Bsa29I, BseCI, BspDI, BspXI, Bst28I, BstNZ169I, BsuTUI, LplI

Bsr - Bss[]

Enzyme PDB code Source Recognition sequence Cut Isoschizomers
Bacillus stearothermophilus 5' ACTGG
3' TGACC
5' ---ACTGGN   --- 3'
3' ---TGAC   CN--- 5'
Bacillus stearothermophilus CPW7 5' GGWCC
3' CCWGG
5' ---G   GWCC--- 3'
3' ---CCWG   G--- 5'
BamNxI, BcuAI, Csp68KI, Eco47I, FssI, HgiCII, HgiJI, SinI
Bacillus stearothermophilus CPW193 5' CCGCTC
3' GGCGAG
5' ---CCG   CTC--- 3'
3' ---GGC   GAG--- 5'
AccBSI, BstD102I, Bst31NI, MbiI
Bacillus stearothermophilus BR 5' GATN4ATC
3' CTAN4TAG
5' ---GATNN   NNATC--- 3'
3' ---CTANN   NNTAG--- 5'
Bacillus stearothermophilus D70 5' GCAATG
3' CGTTAC
5' ---GCAATGNN   --- 3'
3' ---CGTTAC   NN--- 5'
Bacillus stearothermophilus CPW16 5' RCCGGY
3' YGGCCR
5' ---R   CCGGY--- 3'
3' ---YGGCC   R--- 5'
Bacillus stearothermophilus GR75 5' TGTACA
3' ACATGT
5' ---T   GTACA--- 3'
3' ---ACATG   T--- 5'
AauI,  BsmRI,  Bsp1407I, BstAUI,
Ssp4800I, SspBI
Bacillus stearothermophilus CPW19 5' ACTGG
3' TGACC
5' ---ACTGGN   --- 3'
3' ---TGAC   CN--- 5'
Bacillus sp. 5' RCCGGY
3' YGGCCR
5' ---R   CCGGY--- 3'
3' ---YGGCC   R--- 5'
Bacillus stearothermophilus EC 5' CCNNGG
3' GGNNCC
5' ---C   CNNGG--- 3'
3' ---GGNNC   C--- 5'
Bacillus stearothermophilus H3 5' CTCGAG
3' GAGCTC
5' ---C   TCGAG--- 3'
3' ---GAGCT   C--- 5'
AbrI, BluI, BstVI, PanI, SauLPII, SciI, SlaI, StrI, TliI
Bacillus stearothermophilus H3 5' GCGCGC
3' CGCGCG
5' ---G   CGCGC--- 3'
3' ---CGCGC   G--- 5'
Bacillus stearothermophilus IM 5' GGGTC
3' CCCAG
5' ---GG   GTC--- 3'
3' ---CCCAG   --- 5'
Bacillus stearothermophilus TBI 5' CCNGG
3' GGNCC
5' ---   CCNGG--- 3'
3' ---GGNCC   --- 5'
Bacillus stearothermophilus NA 5' GTATAC
3' CATATG
5' ---GTA   TAC--- 3'
3' ---CAT   ATG--- 5'
Bacillus sphaericus KTN 5' GRCGYC
3' CYGCRG
5' ---GR   CGYC--- 3'
3' ---CYGC   RG--- 5'
AcyI, AhaII, AosII, AstWI, AsuIII, BsaHI, HgiI, Hsp92I, Msp17I
Bacillus stearothermophilus S719 5' CACGAG
3' GTGCTC
5' ---C   ACGAG--- 3'
3' ---GTGCT   C--- 5'
Bacillus stearothermophilus T1 5' CCWWGG
3' GGWWCC
5' ---C   CWWGG--- 3'
3' ---GGWWC   C--- 5'

Notes[]

  1. ^ Smith HO, Nathans D (December 1973). "Letter: A suggested nomenclature for bacterial host modification and restriction systems and their enzymes". J. Mol. Biol. 81 (3): 419–23. doi:10.1016/0022-2836(73)90152-6. PMID 4588280.
  2. ^ Roberts RJ, Belfort M, Bestor T, Bhagwat AS, Bickle TA, Bitinaite J, Blumenthal RM, Degtyarev SK, Dryden DT, Dybvig K, Firman K, Gromova ES, Gumport RI, Halford SE, Hattman S, Heitman J, Hornby DP, Janulaitis A, Jeltsch A, Josephsen J, Kiss A, Klaenhammer TR, Kobayashi I, Kong H, Krüger DH, Lacks S, Marinus MG, Miyahara M, Morgan RD, Murray NE, Nagaraja V, Piekarowicz A, Pingoud A, Raleigh E, Rao DN, Reich N, Repin VE, Selker EU, Shaw PC, Stein DC, Stoddard BL, Szybalski W, Trautner TA, Van Etten JL, Vitor JM, Wilson GG, Xu SY (April 2003). "A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes". Nucleic Acids Res. 31 (7): 1805–12. doi:10.1093/nar/gkg274. PMC 152790. PMID 12654995.
  3. ^ Jeremy MB, John LT, Lubert S (2002). "3. Protein Structure and Function". Biochemistry. San Francisco: W. H. Freeman. ISBN 0-7167-4684-0.
  4. ^ Anfinsen C.B. (1973). "Principles that Govern the Folding of Protein Chains". Science. 181 (4096): 223–30. doi:10.1126/science.181.4096.223. PMID 4124164.
  5. ^ Kessler C, Manta V (August 1990). "Specificity of restriction endonucleases and DNA modification methyltransferases a review (Edition 3)". Gene. 92 (1–2): 1–248. doi:10.1016/0378-1119(90)90486-B. PMID 2172084.
  6. ^ Pingoud A, Jeltsch A (September 2001). "Structure and function of type II restriction endonucleases". Nucleic Acids Res. 29 (18): 3705–27. doi:10.1093/nar/29.18.3705. PMC 55916. PMID 11557805.
  7. ^ Kachalova GS, Rogulin EA, Yunusova AK, Artyukh RI, Perevyazova TA, Matvienko NI, Zheleznaya LA, Bartunik HD (December 2008). "Structural analysis of the heterodimeric type IIS restriction endonuclease R.BspD6I acting as a complex between a monomeric site-specific nickase and a catalytic subunit". J Mol Biol. 384 (2): 489–502. doi:10.1016/j.jmb.2008.09.033. PMID 18835275.
  8. ^ Kachalova GS, Rogulin EA, Yunusova AK, Artyukh RI, Perevyazova TA, Matvienko NI, Zheleznaya LA, Bartunik HD (September 2007). "Crystallization and preliminary X-ray diffraction analysis of the small subunit of the heterodimeric restriction endonuclease R.BspD6I". Acta Crystallogr F. 63 (Pt 9): 795–7. doi:10.1107/S174430910704016X. PMC 2376331. PMID 17768358.
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