Magnesium bromide

From Wikipedia, the free encyclopedia
Magnesium bromide[1]
Cadmium-iodide-3D-balls.png
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.029.246 Edit this at Wikidata
UNII
  • InChI=1S/2BrH.Mg/h2*1H;/q;;+2/p-2 checkY
    Key: OTCKOJUMXQWKQG-UHFFFAOYSA-L checkY
  • InChI=1/2BrH.Mg/h2*1H;/q;;+2/p-2
    Key: OTCKOJUMXQWKQG-NUQVWONBAY
  • [Mg+2].[Br-].[Br-]
Properties
MgBr2 (anhydrous)
MgBr2·6H2O (hexahydrate)
Molar mass 184.113 g/mol (anhydrous)
292.204 g/mol (hexahydrate)
Appearance white hygroscopic hexagonal crystals (anhydrous) colorless monoclinic crystals (hexahydrate)
Density 3.72 g/cm3 (anhydrous)
2.07 g/cm3 (hexahydrate)
Melting point 711 °C (1,312 °F; 984 K) 172.4 °C, decomposes (hexahydrate)
Boiling point 1,250 °C (2,280 °F; 1,520 K)
102 g/100 mL (anhydrous)
316 g/100 mL (0 °C, hexahydrate)
Solubility ethanol: 6.9 g/100 mL
methanol: 21.8 g/100 mL
−72.0·10−6 cm3/mol
Structure
Rhombohedral, hP3
P-3m1, No. 164
octahedral
Thermochemistry
70 J/mol K
117.2 J·mol−1·K−1
Std enthalpy of
formation (ΔfH⦵298)
 -524.3 kJ·mol−1
Hazards
NFPA 704 (fire diamond)
1
0
0
Safety data sheet (SDS) External SDS
Related compounds
Other anions
 magnesium fluoride
magnesium chloride
magnesium iodide
Other cations
 Beryllium bromide
Calcium bromide
Strontium bromide
Barium bromide
Radium bromide
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N  (what is checkY☒N ?)
Infobox references

Magnesium bromide (MgBr2) is a chemical compound of magnesium and bromine that is white and deliquescent. It is often used as a mild sedative and as an anticonvulsant for treatment of nervous disorders.[2] It is water-soluble and somewhat soluble in alcohol. It can be found naturally in small amounts in some minerals such as: bischofite and carnallite, and in sea water, such as that of the Dead Sea.[3][4]

Synthesis[]

Magnesium bromide can be synthesized by reacting hydrobromic acid with magnesium oxide and crystallizing the product.[4] It can also be made by reacting magnesium carbonate and hydrobromic acids, and collecting the solid left after evaporation.[3]

Uses[]

Magnesium bromide is used as a catalyst for many reactions, the first being a solvent-free one-pot synthesis of dihydropyrimidinones, which are often used in the pharmaceutical world in medications such as calcium channel blockers and HIVgp-120-CD4 inhibitors.[5] It also has been used as a tranquilizer.[3] Magnesium bromide in combination with CH2Cl2 catalyzes a reaction that causes specific symmetry and chiral centers through hydrogenation of alkenes.[6] Magnesium bromide when bonded to other functional groups has shown more practical uses other than catalyzing reactions. When bonded to an ethyl group it is used for regiospecific analysis of triglycerols.[7] Magnesium bromide hexahydrate is being worked with to be used as a flame retardant. It was found that if 0.125 mol/L of magnesium bromide hexahydrate was added to a cotton material it acted as a flame retardant.[8] Magnesium bromide was used to synthesize the first stable magnesium silylenoid. A silylenoid is a compound that contains R2SiMX (M is metal and R is an organic moiety). Traditionally only lithium, potassium, and sodium could be used. The magnesium silylenoid is synthesized through the addition of magnesium bromide to lithium lithium methyl bromosilylenoid. The magnesium atom replaces the lithium in the complex and has a bromide attached to it. This complex is stable at room temperature.[9]

References[]

  1. ^ Lide, David R. (1998). Handbook of Chemistry and Physics (87 ed.). Boca Raton, Florida: CRC Press. pp. 4–67. ISBN 0-8493-0594-2.
  2. ^ Pradyot Patnaik. Handbook of Inorganic Chemicals. McGraw-Hill, 2002, ISBN 0-07-049439-8
  3. ^ a b c Gruyter, W. Concise Encyclopedia Chemistry, Walter de Gruyter & Company: Berlin, 1993; 612
  4. ^ a b Lewis, R.J. Hawley’s Condensed Chemical Dictionary, 15th ed.; John Wiley &Sons Inc.:New York, 2007; 777
  5. ^ Salehi, Hojatollah; Guo, Qing‐Xiang (2004). "A Facile and Efficient One‐Pot Synthesis of Dihydropyrimidinones Catalyzed by Magnesium Bromide Under Solvent‐Free Conditions". Synthetic Communications. 34 (1): 171. doi:10.1081/SCC-120027250. S2CID 98003817.
  6. ^ Bouzide, Abderrahim (2002). "Magnesium Bromide Mediated Highly Diastereoselective Heterogeneous Hydrogenation of Olefins". Organic Letters. 4 (8): 1347–50. doi:10.1021/ol020032m. PMID 11950359.
  7. ^ Ando, Y; Tomita, Y; Haba, Y. Preparation of Ethyl Magnesium Bromide for Regiospecific Analysis of Triacylglycerols Journal of Oleo Science, 2008, 57, 459
  8. ^ Mostashari, S. M.; Fayyaz, F. (2008). "XRD characterization of the ashes from a burned cellulosic fabric impregnated with magnesium bromide hexahydrate as flame-retardant". Journal of Thermal Analysis and Calorimetry. 92 (3): 845. doi:10.1007/s10973-007-8928-4. S2CID 94416902.
  9. ^ Lim, Young Mook; Cho, Hyeon Mo; Lee, Myong Euy; Baeck, Kyoung Koo (2006). "A Stable Magnesium Bromosilylenoid: Transmetalation of a Lithium Bromosilylenoid by Magnesium Bromide". Organometallics. 25 (21): 4960. doi:10.1021/om060589w.
Retrieved from ""