From Wikipedia, the free encyclopedia
Mannosulfan Other names [(2R ,3S ,4S ,5R )-3,4-dihydroxy-2,5,6-tris(methylsulfonyloxy)hexyl] methanesulfonate ATC code
1,2,5,6-Tetrakis-O-(methylsulfonyl)-D -mannitol
CAS Number PubChem CID ChemSpider UNII Formula C 10 H 22 O 14 S 4 Molar mass 494.51 g·mol−1 3D model (JSmol )
CS(=O)(=O)OC[C@H]([C@H]([C@@H]([C@@H](COS(=O)(=O)C)OS(=O)(=O)C)O)O)OS(=O)(=O)C
InChI=1S/C10H22O14S4/c1-25(13,14)21-5-7(23-27(3,17)18)9(11)10(12)8(24-28(4,19)20)6-22-26(2,15)16/h7-12H,5-6H2,1-4H3/t7-,8-,9-,10-/m1/s1
Key:UUVIQYKKKBJYJT-ZYUZMQFOSA-N
Mannosulfan (INN ) is an alkylating agent with the potential for the treatment of cancer . It is not approved by the United States FDA for cancer treatment. Research suggests it is less toxic than the alkyl sulfonate Busulfan .[1]
References [ ]
^ Jeswani G, Paul SD (2017). "Recent Advances in the Delivery of Chemotherapeutic Agents". Nano- and Microscale Drug Delivery Systems . pp. 281–98. doi :10.1016/B978-0-323-52727-9.00015-7 . ISBN 978-0-323-52727-9 .
External links [ ]
Intracellular
chemotherapeutic agents /
antineoplastic agents (
L01 )
SPs /MIs (M phase )
Block microtubule assembly Block microtubule disassembly
DNA replication inhibitor
Photosensitizers /PDT Other
Enzyme inhibitors Receptor antagonists Other/ungrouped
# WHO-EM
‡ Withdrawn from market
Clinical trials :
† Phase III
§ Never to phase III
By consumption
Alcohols found inalcoholic drinks
1-Propanol
2-Methyl-1-butanol
Ethanol
Isoamyl alcohol
Isobutanol
Phenethyl alcohol
tert -Amyl alcohol
tert -Butyl alcohol
Tryptophol
Medical alcohol Toxic alcohols
Isopropyl alcohol
Methanol
Primary alcohols (1°)
Methanol Ethanol Butanol Straight-chain saturated C1 — C9
Methanol
Ethanol
1-Propanol
1-Butanol
1-Pentanol
1-Hexanol
1-Heptanol
1-Octanol (capryl)
1-Nonanol (pelargonic)
Straight-chain saturated C10 — C19
1-Decanol (capric)
1-Undecanol (hendecyl)
1-Dodecanol (lauryl)
1-Tridecanol
1-Tetradecanol (myristyl)
1-Pentadecanol
1-Hexadecanol (cetyl / palmityl)
1-Heptadecanol
1-Octadecanol (stearyl)
1-Nonadecanol
Straight-chain saturated C20 — C29 Straight-chain saturated C30 — C39 Straight-chain saturated C40 — C49
Secondary alcohols (2°) Tertiary alcohols (3°) Hydric alcohols
Monohydric alcohols
Methanol
Ethanol
Isopropanol
Dihydric alcohols
Ethylene glycol
Propylene glycol
Trihydric alcohols Polyhydric alcohols
Amyl alcohols
2,2-Dimethylpropan-1-ol
2-Methylbutan-1-ol
2-Methylbutan-2-ol
3-Methylbutan-1-ol
3-Methylbutan-2-ol
Pentan-1-ol
Pentan-2-ol
Pentan-3-ol
Aromatic alcohols Saturatedfatty alcohols Branched and unsaturatedfatty alcohols Sugar alcohols
C2 — C7 Deoxy sugar alcohols Cyclic sugar alcohols Glycylglycitols
Terpene alcohols
Monoterpene alcohols
Borneol
Citronellol
Geraniol
Linalool
Menthol
Nerol
Rhodinol
Terpineol
Sesquiterpene alcohols Diterpene alcohols
Dialcohols Trialcohols Sterols
Cholesterol
Ergosterol
Lanosterol
β-Sitosterol
Stigmasterol
Fluoroalcohols Preparations Reactions
Category
Categories :
Alkylsulfonates Mesylate esters Monosaccharides Alkylating antineoplastic agents Sugar alcohols Antineoplastic and immunomodulating drug stubs Hidden categories:
Articles without EBI source Chemical pages without DrugBank identifier Articles without KEGG source Drugs with no legal status Commons category link from Wikidata All stub articles