From Wikipedia, the free encyclopedia
Mitoguazone |
|
|
Other names | 2-[[(1E)-1-(Diaminomethylidenehydrazinylidene)propan-2-ylidene]amino]guanidine |
---|
ATC code | |
---|
|
(2E,2'E)-2,2'-(1E,2E)-propane-1,2-diylidenedihydrazinecarboximidamide
|
CAS Number | |
---|
PubChem CID | |
---|
ChemSpider | |
---|
UNII | |
---|
KEGG | |
---|
ChEBI | |
---|
CompTox Dashboard (EPA) | |
---|
ECHA InfoCard | 100.121.515 |
---|
|
Formula | C5H12N8 |
---|
Molar mass | 184.207 g·mol−1 |
---|
3D model (JSmol) | |
---|
C\C(\C=N\NC(N)=N)=N/NC(N)=N
|
InChI=1S/C5H12N8/c1-3(11-13-5(8)9)2-10-12-4(6)7/h2H,1H3,(H4,6,7,12)(H4,8,9,13)/b10-2+,11-3+ NKey:PKDBCJSWQUOKDO-UHFFFAOYSA-M N
|
NY (what is this?) |
Mitoguazone (also known as methylglyoxal bis(guanylhydrazone) or MGBG) is a drug used in chemotherapy.[1]
References[]
- ^ Hoffmann H, Gutsche W, Amlacher R, Schulze W, Werner W, Lenk H, Wohlrab W, Haupt E (1989). "[Mitoguazone (methylglyoxal bis(guanylhydrazone))--its status and prospects]". Archiv Fur Geschwulstforschung (in German). 59 (2): 135–48. PMID 2655552.
Intracellular chemotherapeutic agents / antineoplastic agents ( L01) |
---|
SPs/MIs (M phase) | Block microtubule assembly | |
---|
Block microtubule disassembly | |
---|
|
---|
DNA replication inhibitor | |
---|
Photosensitizers/PDT | |
---|
Other | |
---|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
|
Categories:
- Guanidines
- Antineoplastic drugs
- Antineoplastic and immunomodulating drug stubs
Hidden categories:
- CS1 German-language sources (de)
- Articles with changed ChemSpider identifier
- Articles with changed EBI identifier
- ECHA InfoCard ID from Wikidata
- Articles with changed InChI identifier
- Chemical pages without DrugBank identifier
- Drugs with no legal status
- Drugboxes which contain changes to verified fields
- Drugboxes which contain changes to watched fields
- All stub articles