Phosphoenolpyruvate carboxykinase (diphosphate)
| Phosphoenolpyruvate carboxykinase (diphosphate) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Phosphoenolpyruvate carboxykinase (pyrophosphate) homodimer, Actinomyces israelii | |||||||||
| Identifiers | |||||||||
| EC no. | 4.1.1.38 | ||||||||
| CAS no. | 2598306 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Phosphoenolpyruvate carboxykinase (diphosphate) (EC 4.1.1.38, phosphopyruvate carboxylase, phosphoenolpyruvate carboxylase, PEP carboxyphosphotransferase, PEP carboxykinase, phosphopyruvate carboxykinase (pyrophosphate), PEP carboxylase, phosphoenolpyruvic carboxykinase, phosphoenolpyruvic carboxylase, phosphoenolpyruvate carboxykinase, phosphoenolpyruvate carboxytransphosphorylase, phosphoenolpyruvate carboxykinase, phosphoenolpyruvic carboxykinase, PEPCTrP, phosphoenolpyruvic carboxykinase (pyrophosphate), phosphoenolpyruvic carboxylase (pyrophosphate), phosphoenolpyruvate carboxyphosphotransferase, phosphoenolpyruvic carboxytransphosphorylase, phosphoenolpyruvate carboxylase (pyrophosphate), phosphopyruvate carboxylase (pyrophosphate), diphosphate:oxaloacetate carboxy-lyase (transphosphorylating)) is an enzyme with systematic name diphosphate:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming).[1] This enzyme catalyses the following chemical reaction
- diphosphate + oxaloacetate phosphate + phosphoenolpyruvate + CO2
This enzyme also catalyses the reaction:
- phosphoenolpyruvate + GTP + CO2 pyruvate + GDP.
It is transcriptionally upregulated in the liver by glucagon.
See also[]
References[]
External links[]
- Phosphoenolpyruvate+carboxykinase+(diphosphate) at the US National Library of Medicine Medical Subject Headings (MeSH)
- EC 4.1.1