Phosphonopyruvate hydrolase
Phosphonopyruvate hydrolase | |||||||||
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Identifiers | |||||||||
EC no. | 3.11.1.3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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In enzymology, a phosphonopyruvate hydrolase (EC 3.11.1.3) is an enzyme that catalyzes the chemical reaction
- 3-phosphonopyruvate + H2O pyruvate + phosphate
Thus, the two substrates of this enzyme are and H2O, whereas its two products are pyruvate and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on carbon-phosphorus bonds. The systematic name of this enzyme class is '. This enzyme is also called PPH'.
References[]
- Ternan NG, Hamilton JT, Quinn JP (2000). "Initial in vitro characterisation of phosphonopyruvate hydrolase, a novel phosphate starvation-independent, carbon-phosphorus bond cleavage enzyme in Burkholderia cepacia Pal6". Arch. Microbiol. 173 (1): 35–41. doi:10.1007/s002030050005. PMID 10648102.
- Kulakova AN, Wisdom GB, Kulakov LA, Quinn JP (2003). "The purification and characterization of phosphonopyruvate hydrolase, a novel carbon-phosphorus bond cleavage enzyme from Variovorax sp Pal2". J. Biol. Chem. 278 (26): 23426–31. doi:10.1074/jbc.M301871200. PMID 12697754.
- Dunaway-Mariano D, Herzberg O (2006). "Structure and kinetics of phosphonopyruvate hydrolase from Variovorax sp. Pal2: new insight into the divergence of catalysis within the PEP mutase/isocitrate lyase superfamily". Biochemistry. 45 (38): 11491–504. doi:10.1021/bi061208l. PMID 16981709.
Categories:
- EC 3.11.1
- Enzymes of unknown structure
- Hydrolase stubs