Telmisartan/amlodipine
| Combination of | |
|---|---|
| Telmisartan | Angiotensin II receptor antagonist |
| Amlodipine | Calcium channel blocker |
| Clinical data | |
| Trade names | Twynsta, others |
| Routes of administration | By mouth |
| Legal status | |
| Legal status |
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| Identifiers | |
| CAS Number | |
Telmisartan/amlodipine, sold under the brand name Twynsta among others, is a medication used to treat high blood pressure.[1] It is a combination of telmisartan an angiotensin II receptor antagonist with amlodipine a calcium channel blocker.[1] It is taken by mouth.[1]
Common side effects include dizziness, swelling, and back pain.[1] Severe side effects may include low blood pressure, kidney problems, electrolyte problems, and a heart attack.[1] Use during pregnancy may harm the baby.[1] Telmisartan works by blocking the effects of angiotensin II while amlodipine works by decreasing calcium ion entry into smooth muscle and heart muscle.[1]
The combination was approved for medical use in the United States in 2009.[1] The combination is on the World Health Organization's List of Essential Medicines.[2] It is available as a generic medication.[3]
References[]
- ^ a b c d e f g h "DailyMed - TELMISARTAN AND AMLODIPINE tablet". dailymed.nlm.nih.gov. Retrieved 30 October 2019.
- ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ^ "Telmisartan and Amlodipine (Professional Patient Advice)". Drugs.com. Retrieved 30 October 2019.
External links[]
- "Amlodipine besylate mixture with telmisartan". Drug Information Portal. U.S. National Library of Medicine.
- Combination drugs