Acetate kinase (diphosphate)
| acetate kinase (diphosphate) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.2.12 | ||||||||
| CAS no. | 57657-58-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an acetate kinase (diphosphate) (EC 2.7.2.12) is an enzyme that catalyzes the chemical reaction
- diphosphate + acetate phosphate + acetyl phosphate
Thus, the two substrates of this enzyme are diphosphate and acetate, whereas its two products are phosphate and .
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. The systematic name of this enzyme class is diphosphate:acetate phosphotransferase. This enzyme is also called pyrophosphate-acetate phosphotransferase. This enzyme participates in pyruvate metabolism.
References[]
- Reeves RE, Guthrie JD (1975). "Acetate kinase (pyrophosphate). A fourth pyrophosphate-dependent kinase from Entamoeba histolytica". Biochem. Biophys. Res. Commun. 66 (4): 1389–95. doi:10.1016/0006-291X(75)90513-6. PMID 172079.
Categories:
- EC 2.7.2
- Enzymes of unknown structure
- EC 2.7 stubs