Ciclindole
From Wikipedia, the free encyclopedia
Clinical data | |
---|---|
Routes of administration | Oral |
ATC code |
|
Legal status | |
Legal status |
|
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEMBL | |
Chemical and physical data | |
Formula | C14H18N2 |
Molar mass | 214.312 g·mol−1 |
3D model (JSmol) | |
SMILES
|
Ciclindole (INN; WIN-27,147-2), also known as cyclindole (USAN), is an antipsychotic with a tricyclic structure that was never marketed.[1][2] It displaces spiperone binding in vitro and elevates dopamine levels in the striatum, indicating it acts as a D2 receptor antagonist.[2]
Synthesis[]
See also[]
- Flucindole
- frovatriptan
- alpha-N,N-Trimethyltryptamine
- Iprindole
References[]
- ^ Triggle DJ (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. ISBN 0-412-46630-9.
- ^ a b Wood PL, McQuade PS (1984). "Ciclindole and flucindole: novel tetrahydrocarbazolamine neuroleptics". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 8 (4–6): 773–7. doi:10.1016/0278-5846(84)90057-5. PMID 6152347. S2CID 39252411.
Antipsychotics (N05A) | |
---|---|
Typical |
|
Disputed |
|
Atypical |
|
Others |
|
|
Dopamine receptor modulators | |||||||
---|---|---|---|---|---|---|---|
D1-like |
| ||||||
D2-like |
| ||||||
|
Tricyclics | |
---|---|
Classes |
|
Antidepressants (TCAs and TeCAs) |
|
Antihistamines |
|
Antipsychotics |
|
Anticonvulsants |
|
Others |
|
Retrieved from ""
Categories:
- Drugs not assigned an ATC code
- Dimethylamino compounds
- Antipsychotics
- Carbazoles
- Tricyclic antidepressants
Hidden categories:
- Drugs with non-standard legal status
- Chemical pages without DrugBank identifier
- Articles without InChI source
- Articles containing unverified chemical infoboxes