Dolichyl-diphosphate—polyphosphate phosphotransferase

In enzymology, a dolichyl-diphosphate-polyphosphate phosphotransferase (EC 2.7.4.20) is an enzyme that catalyzes the chemical reaction

dolichyl diphosphate + (phosphate)n ${\displaystyle \rightleftharpoons }$ dolichyl phosphate + (phosphate)n⁺1

Thus, the two substrates of this enzyme are and (phosphate)n, whereas its two products are dolichyl phosphate and (phosphate)n+1.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is dolichyl-diphosphate:polyphosphate phosphotransferase. This enzyme is also called dolichylpyrophosphate:polyphosphate phosphotransferase.

References[]

• Naumov AV, Shabalin YA, Vagabov VM, Kulaev IS. "Two pathways of dephosphorylation of dolichyl diphosphate in yeasts". Biochemistry. Moscow. 50: 551–556.