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Main article: Dihydroergocryptine
Epicriptine Other names beta -DihydroergocryptinePregnancy category Routes of administration Oral ATC code Legal status
In general: ℞ (Prescription only)
(2R ,4R ,7R )-N - [(1S ,2S ,4R ,7S )- 2-hydroxy- 7-(S )-(1-methylpropyl)- 5,8-dioxo- 4-(propan-2-yl)- 3-oxa- 6,9-diazatricyclo [7.3.0.02,6 ]dodecan-4-yl]- 6-methyl- 6,11-diazatetracyclo [7.6.1.02,7 .012,16 ] hexadeca- 1(16),9,12,14-tetraene- 4-carboxamide
CAS Number PubChem CID ChemSpider UNII ChEBI ChEMBL CompTox Dashboard (EPA ) ECHA InfoCard 100.039.157 Formula C 32 H 43 N 5 O 5 Molar mass 577.726 g·mol−1 3D model (JSmol )
CCC(C)[C@H]1C(=O)N2CCC[C@H]2[C@]3(N1C(=O)[C@](O3)(C(C)C)NC(=O)[C@@H]4C[C@H]5[C@@H](CC6=CNC7=CC=CC5=C67)N(C4)C)O
InChI=1S/C32H43N5O5/c1-6-18(4)27-29(39)36-12-8-11-25(36)32(41)37(27)30(40)31(42-32,17(2)3)34-28(38)20-13-22-21-9-7-10-23-26(21)19(15-33-23)14-24(22)35(5)16-20/h7,9-10,15,17-18,20,22,24-25,27,33,41H,6,8,11-14,16H2,1-5H3,(H,34,38)/t18?,20-,22-,24-,25+,27+,31-,32+/m1/s1
Key:SBFXHXZNBNFPHV-CROXOCCCSA-N
Epicriptine or beta -dihydroergocryptine is a dopamine agonist of the ergoline class. It constitutes one third of the mixture known as dihydroergocryptine , the other two thirds consisting of alpha -dihydroergocryptine. The alpha differs from the beta form only in the position of a single methyl group, which is a consequence of the biosynthesis in which the proteinogenic amino acid isoleucine is replaced by leucine .[1]
References [ ]
^ Steinhilber D, Schubert-Zsilavecz M, Roth HJ (2005). Medizinische Chemie (in German). Stuttgart: Deutscher Apotheker Verlag. p. 142. ISBN 3-7692-3483-9 .
D1 -like
Agonists
Ergolines : Cabergoline
CY-208,243
Dihydroergocryptine
Lisuride
Pergolide
Terguride
PAMs Antagonists
D2 -like
See also: Receptor/signaling modulators
Adrenergics
Serotonergics
Monoamine reuptake inhibitors
Monoamine releasing agents
Monoamine metabolism modulators
Monoamine neurotoxins
Ergolines
Lysergic acid derivativesPsychedelic lysergamides Clavines Other ergolines Natural sources
Achnatherum robustum (Sleepy Grass)
Claviceps spp. (Ergot)
Morning glory: Argyreia nervosa (Hawaiian Baby Woodrose), Ipomoea spp. (Morning Glory, Tlitliltzin, Badoh Negro), Rivea corymbosa (Coaxihuitl, Ololiúqui)
Categories :
Dopamine agonists Oxazolopyrrolopyrazines Lactams Ergot alkaloids Lysergamides Isopropyl compounds Nervous system drug stubs Hidden categories:
CS1 German-language sources (de) Drugs with non-standard legal status ECHA InfoCard ID from Wikidata Chemical pages without DrugBank identifier Articles without KEGG source Articles containing unverified chemical infoboxes All stub articles