Nafadotride
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IUPAC name
N-{[(2S)-1-butylpyrrolidin-2-yl]methyl}-4-cyano-1-methoxy-2-naphthamide
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Identifiers | |
3D model (JSmol)
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ChEMBL | |
IUPHAR/BPS
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MeSH | Nafadotride |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
Chemical formula
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C22H27N3O2 |
Molar mass | 365.477 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
what is ?) | (|
Infobox references | |
Nafadotride is a dopamine antagonist with reasonable selectivity for the D3 subtype (9.6 times selectivity for D3 over D2).[1]
References[]
- ^ Pilla M, Perachon S, Sautel F, Garrido F, Mann A, Wermuth CG, Schwartz JC, Everitt BJ, Sokoloff P. Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 agonist. Nature. 1999;400:371–375.
Categories:
- Dopamine antagonists
- Pyrrolidines
- Carboxamides
- Nitriles
- Naphthol ethers
- Nervous system drug stubs