Dixyrazine
Names
IUPAC name
(RS )-2-[2-[4-(2-methyl-3-phenothiazin-10-ylpropyl)piperazin-1-yl]ethoxy]ethanol
Other names
UCB-3412
Identifiers
CAS Number
3D model (JSmol )
ChemSpider
ECHA InfoCard
100.017.811
EC Number
KEGG
UNII
InChI=1S/C24H33N3O2S/c1-20(18-26-12-10-25(11-13-26)14-16-29-17-15-28)19-27-21-6-2-4-8-23(21)30-24-9-5-3-7-22(24)27/h2-9,20,28H,10-19H2,1H3
N Key: MSYUMPGNGDNTIQ-UHFFFAOYSA-N
N InChI=1/C24H33N3O2S/c1-20(18-26-12-10-25(11-13-26)14-16-29-17-15-28)19-27-21-6-2-4-8-23(21)30-24-9-5-3-7-22(24)27/h2-9,20,28H,10-19H2,1H3
Key: MSYUMPGNGDNTIQ-UHFFFAOYAI
CC(CN1CCN(CC1)CCOCCO)CN2C3=CC=CC=C3SC4=CC=CC=C42
Properties
Chemical formula
C24 H33 N3 O2 S
Molar mass
427.60272 g/mol
Pharmacology
ATC code
N05AB01 (WHO )
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N (what is Y N ?)
Infobox references
Chemical compound
Dixyrazine , also known as dixypazin (oxalate ), sold under the brand names Ansiolene , Esocalm , Esucos , Metronal , and Roscal , is a typical antipsychotic of the phenothiazine group described as a neuroleptic and antihistamine .[1] It was first introduced in Germany in 1969. It is used as a neuroleptic, anxiolytic , and antihistamine in doses between 12.5 and 75 mg a day.
References [ ]
Antipsychotics (N05A )
Typical Disputed
Butyrophenones : Melperone
Atypical
Butyrophenones : Lumateperone
Phenylpiperazines /quinolinones : Aripiprazole
Brilaroxazine †
Brexpiprazole
Cariprazine
Others
Monoamine-depleting agents : Oxypertine
Reserpine
Tetrabenazine
# WHO-EM
‡ Withdrawn from market
Clinical trials :
† Phase III
§ Never to phase III
D1 -like
Agonists
Ergolines : Cabergoline
CY-208,243
Dihydroergocryptine
Lisuride
Pergolide
Terguride
PAMs Antagonists
D2 -like
Agonists
Adamantanes : Amantadine
Memantine
Rimantadine
Ergolines : Bromocriptine
Cabergoline
Chanoclavine
Dihydroergocryptine
Epicriptine
Ergocornine
Lergotrile
Lisuride
LSD
Pergolide
Terguride
Atypical antipsychotics : Alentemol (U-66444B)
Aripiprazole (+sertraline )
Aripiprazole lauroxil
Bifeprunox
Brexpiprazole
Brilaroxazine
Cariprazine
F-15063
Lumateperone
Norclozapine
Antagonists
Antidepressants : Amoxapine
Nefazodone
Opipramol
Propiomazine
Trimipramine
See also: Receptor/signaling modulators
Adrenergics
Serotonergics
Monoamine reuptake inhibitors
Monoamine releasing agents
Monoamine metabolism modulators
Monoamine neurotoxins
H1
Agonists
2-Pyridylethylamine
Betahistine
Histamine
HTMT
L -Histidine
UR-AK49
Antagonists
Others: Atypical antipsychotics (e.g., aripiprazole , asenapine , brexpiprazole , brilaroxazine , clozapine , iloperidone , olanzapine , paliperidone , quetiapine , risperidone , ziprasidone , zotepine )
Phenylpiperazine antidepressants (e.g., hydroxynefazodone , nefazodone , trazodone , triazoledione )
Tetracyclic antidepressants (e.g., amoxapine , loxapine , maprotiline , mianserin , mirtazapine , oxaprotiline )
Tricyclic antidepressants (e.g., amitriptyline , butriptyline , clomipramine , desipramine , dosulepin (dothiepin) , doxepin , imipramine , iprindole , lofepramine , nortriptyline , protriptyline , trimipramine )
Typical antipsychotics (e.g., chlorpromazine , flupenthixol , fluphenazine , loxapine , perphenazine , prochlorperazine , thioridazine , thiothixene )
H2
H3
Agonists
α-Methylhistamine
Cipralisant
Histamine
Imetit
Immepip
Immethridine
L -Histidine
Methimepip
Proxyfan
Antagonists
H4
Agonists
4-Methylhistamine
α-Methylhistamine
Histamine
L -Histidine
OUP-16
VUF-8430
Antagonists
See also: Receptor/signaling modulators • Monoamine metabolism modulators • Monoamine reuptake inhibitors