Isomaltulose synthase
| isomaltulose synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 5.4.99.11 | ||||||||
| CAS no. | 159940-49-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an isomaltulose synthase (EC 5.4.99.11) is an enzyme that catalyzes the chemical reaction
- sucrose 6-O-Alpha-D-Glucopyranosyl-D-Fructofuranose
Hence, this enzyme has one substrate, sucrose, and one product, 6-O-Alpha-D-Glucopyranosyl-D-Fructofuranose.
This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring other groups. The systematic name of this enzyme class is sucrose glucosylmutase. Other names in common use include isomaltulose synthetase, sucrose alpha-glucosyltransferase, and trehalulose synthase.
Structural studies[]
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1M53, 1ZJA, 1ZJB, 2PWD, 2PWE, 2PWF, and 2PWG.
References[]
- Cheetham PS (1984). "The extraction and mechanism of a novel isomaltulose-synthesizing enzyme from Erwinia rhapontici". Biochem. J. 220 (1): 213–20. doi:10.1042/bj2200213. PMC 1153612. PMID 6743261.
- Cheetham PS, Imber CE, Isherwood J (1982). "The formation of isomaltulose by immobilized Erwinia rhapontici". Nature. 299 (5884): 628–631. Bibcode:1982Natur.299..628C. doi:10.1038/299628a0. S2CID 4355243.
Categories:
- EC 5.4.99
- Enzymes of known structure
- Isomerase stubs