Thiamine-triphosphatase
| thiamin triphosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.6.1.28 | ||||||||
| CAS no. | 9068-47-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
| thiamine triphosphatase | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | THTPA | ||||||
| NCBI gene | 79178 | ||||||
| HGNC | 18987 | ||||||
| RefSeq | NM_024328 | ||||||
| UniProt | Q9BU02 | ||||||
| Other data | |||||||
| EC number | 3.6.1.28 | ||||||
| Locus | Chr. 14 q11.2 | ||||||
| |||||||
Thiamine-triphosphatase is an enzyme involved in thiamine metabolism. It catalyzes the chemical reaction
- thiamine triphosphate + H2O thiamine diphosphate + phosphate
This enzyme belongs to the family of acid anhydride hydrolases, specifically those acting on phosphorus-containing anhydrides. Its systematic name is thiamine triphosphate phosphohydrolase.
Structural studies[]
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2JMU.
See also[]
References[]
- Hashitani Y, Cooper JR (1972). "The partial purification of thiamine triphosphatase from rat brain". J. Biol. Chem. 247 (7): 2117–9. doi:10.1016/S0021-9258(19)45498-7. PMID 4335862.
Categories:
- Genes on human chromosome 14
- EC 3.6.1
- Enzymes of known structure
- EC 3.6 stubs