ATC codes
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L Antineoplastic and immunomodulating agents
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L01 Antineoplastic agents
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L02 Endocrine therapy
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L03 Immunostimulants
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L04 Immunosuppressants
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ATC code L02 Endocrine therapy is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.[1][2][3] Subgroup L02 is part of the anatomical group L Antineoplastic and immunomodulating agents.[4]
Codes for veterinary use (ATCvet codes) can be created by placing the letter Q in front of the human ATC code: for example, QL02.[5]
National issues of the ATC classification may include additional codes not present in this list, which follows the WHO version.
L02A Hormones and related agents[]
L02AA Estrogens[]
- L02AA01 Diethylstilbestrol
- L02AA02 Polyestradiol phosphate
- L02AA03 Ethinylestradiol
- L02AA04 Fosfestrol
L02AB Progestogens[]
- L02AB01 Megestrol
- L02AB02 Medroxyprogesterone
- L02AB03 Gestonorone
L02AE Gonadotropin-releasing hormone analogues[]
- L02AE01 Buserelin
- L02AE02 Leuprorelin
- L02AE03 Goserelin
- L02AE04 Triptorelin
- L02AE05 Histrelin
- L02AE51 Leuprorelin and bicalutamide
L02AX Other hormones[]
L02B Hormone antagonists and related agents[]
L02BA Anti-estrogens[]
- L02BA01 Tamoxifen
- L02BA02 Toremifene
- L02BA03 Fulvestrant
L02BB Anti-androgens[]
- L02BB01 Flutamide
- L02BB02 Nilutamide
- L02BB03 Bicalutamide
- L02BB04 Enzalutamide
- L02BB05 Apalutamide
- L02BB06 Darolutamide
L02BG Aromatase inhibitors[]
- L02BG01 Aminogluthetimide
- L02BG02 Formestane
- L02BG03 Anastrozole
- L02BG04 Letrozole
- L02BG05 Vorozole
- L02BG06 Exemestane
L02BX Other hormone antagonists and related agents[]
- L02BX01 Abarelix
- L02BX02 Degarelix
- L02BX03 Abiraterone
- L02BX04 Relugolix
References[]
Androgens and antiandrogens |
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Androgens (incl. AAS) | AR agonists |
- 17α-Ethynyltestosterone derivatives: Danazol
- Gestrinone
- Progestins (e.g., ethisterone (ethynyltestosterone), levonorgestrel, norgestrel, norethisterone (norethindrone), lynestrenol, norgestrienone)
- Tibolone
- Progesterone derivatives: Medroxyprogesterone acetate
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Progonadotropins |
- Antiestrogens (e.g., tamoxifen, clomifene)
- GnRH agonists (e.g., GnRH (gonadorelin), leuprorelin)
- Gonadotropins (e.g., LH, hCG)
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Antiandrogens | AR antagonists | |
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Steroidogenesis inhibitors | |
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Antigonadotropins |
- D2 receptor antagonists (prolactin releasers) (e.g., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)
- Estrogens (e.g., bifluranol, diethylstilbestrol, estradiol, estradiol esters, ethinylestradiol, ethinylestradiol sulfonate, paroxypropione)
- GnRH agonists (e.g., leuprorelin)
- GnRH antagonists (e.g., cetrorelix)
- Progestogens (incl., chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate, gestonorone caproate, medroxyprogesterone acetate, megestrol acetate)
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Others | |
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Estrogens | ER agonists |
- Steroidal: Alfatradiol
- Certain androgens/anabolic steroids (e.g., testosterone, testosterone esters, methyltestosterone, metandienone, nandrolone esters) (via estrogenic metabolites)
- Certain progestins (e.g., norethisterone, noretynodrel, etynodiol diacetate, tibolone)
- Clomestrone
- Cloxestradiol acetate
- Conjugated estriol
- Conjugated estrogens
- Epiestriol
- Epimestrol
- Esterified estrogens
- Estetrol†
- Estradiol
- Estradiol esters (e.g., estradiol acetate, estradiol benzoate, estradiol cypionate, estradiol enanthate, estradiol undecylate, estradiol valerate, polyestradiol phosphate, estradiol ester mixtures (Climacteron))
- Estramustine phosphate
- Estriol
- Estriol esters (e.g., estriol succinate, polyestriol phosphate)
- Estrogenic substances
- Estrone
- Estrone esters
- Ethinylestradiol#
- Hydroxyestrone diacetate
- Mestranol
- Methylestradiol
- Moxestrol
- Nilestriol
- Prasterone (dehydroepiandrosterone; DHEA)
- Promestriene
- Quinestradol
- Quinestrol
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Progonadotropins |
- Antiandrogens (e.g., bicalutamide)
- GnRH agonists (e.g., GnRH (gonadorelin), leuprorelin)
- Gonadotropins (e.g., FSH, LH)
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Antiestrogens | ER antagonists (incl. SERMs/SERDs) |
- Exclusively antagonistic: Fulvestrant
- Noncompetitive inhibitors: Trilostane
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Aromatase inhibitors | |
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Antigonadotropins |
- Androgens/anabolic steroids (e.g., testosterone, testosterone esters, nandrolone esters, oxandrolone, fluoxymesterone)
- D2 receptor antagonists (prolactin releasers) (e.g., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)
- GnRH agonists (e.g., leuprorelin, goserelin)
- GnRH antagonists (e.g., cetrorelix, elagolix)
- Progestogens (e.g., chlormadinone acetate, cyproterone acetate, gestonorone caproate, hydroxyprogesterone caproate, medroxyprogesterone acetate, megestrol acetate)
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Others |
- Mixed mechanism of action: Danazol
- Gestrinone
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
- See also
- Estrogen receptor modulators
- Androgens and antiandrogens
- Progestogens and antiprogestogens
- List of estrogens
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Progestogens (and progestins) | PR agonists |
- Retroprogesterone derivatives: Dydrogesterone
- Trengestone
- Testosterone derivatives: Estranes: Danazol
- Dimethisterone
- Ethisterone
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Antiprogestogens | |
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
- See also
- Progesterone receptor modulators
- Androgens and antiandrogens
- Estrogens and antiestrogens
- List of progestogens
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GnRH modulators (incl. analogues) | |
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Gonadotropins | |
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Others (indirect) | Progonadotropins | |
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Antigonadotropins |
- Sex steroid agonists (via negative feedback on the HPG axis): Androgens/anabolic steroids (e.g., testosterone, nandrolone esters, oxandrolone)
- D2 receptor antagonists (prolactin releasers) (incl., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)
- Estrogens (incl., bifluranol, estradiol, estradiol esters, ethinylestradiol, diethylstilbestrol, paroxypropione)
- Progestogens (incl. progestins, e.g., chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate, gestonorone caproate, medroxyprogesterone acetate, megestrol acetate)
- Others (mixed or unknown mechanism of action): Danazol
- Gestrinone
- Metallibure
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
- See also
- GnRH and gonadotropin receptor modulators
- Androgens and antiandrogens
- Estrogens and antiestrogens
- Progestogens and antiprogestogens
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