Core binding factor
From Wikipedia, the free encyclopedia
The Core binding factor (CBF) is a group of heterodimeric transcription factors.
Core binding factors are composed of:
- a non-DNA-binding CBFβ chain (CBFB)
- a DNA-binding CBFα chain (RUNX1, RUNX2, RUNX3)
References[]
- de Bruijn M, Speck N (2004). "Core-binding factors in hematopoiesis and immune function". Oncogene. 23 (24): 4238–48. doi:10.1038/sj.onc.1207763. PMID 15156179.
External links[]
- Core+Binding+Factors at the US National Library of Medicine Medical Subject Headings (MeSH)
- AI-10-49
Transcription factors and intracellular receptors | |||||||||||||||||||||||||||||||
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see also transcription factor/coregulator deficiencies | |||||||||||||||||||||||||||||||
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