Daf-9
Cytochrome P450 daf-9 | |||||||
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Identifiers | |||||||
Organism | |||||||
Symbol | daf-9 | ||||||
Alt. symbols | CYP22A1 | ||||||
Entrez | 180889 | ||||||
RefSeq (mRNA) | NM_001029732.2 | ||||||
RefSeq (Prot) | NP_001024903.1 | ||||||
UniProt | H2KYS3 | ||||||
Other data | |||||||
Chromosome | X: 6.2 - 6.2 Mb | ||||||
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The Daf-9 gene encodes a cytochrome p450 enzyme catalysis the generation of dafachronic acid (a steroid hormone) in the worm Caenorhabditis elegans,[1] with the CYP Symbol CYP22A1 (Cytochrome P450, family 22, member A1). After generation, dafachronic acid will binding it's nuclear receptor Daf-12 and has been implicated by Cynthia Kenyon and colleagues related to the formation of Dauer larva.[2]
References[]
- ^ Jia K, Albert PS, Riddle DL (2002). "DAF-9, a cytochrome P450 regulating C. elegans larval development and adult longevity". Development. 129 (1): 221–31. PMID 11782415.
- ^ Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R (1993). "A C. elegans mutant that lives twice as long as wild type". Nature. 366 (6454): 461–464. Bibcode:1993Natur.366..461K. doi:10.1038/366461a0. PMID 8247153.
Categories:
- Caenorhabditis elegans genes
- Cytochrome P450