Estradiol/norethisterone acetate

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Estradiol/norethisterone acetate
Combination of
EstradiolEstrogen
Norethisterone acetateProgestogen
Clinical data
Trade namesActivella, Amabelz, CombiPatch, others
AHFS/Drugs.comProfessional Drug Facts
MedlinePlusa601041
Routes of
administration		By mouth
ATC code
Legal status
Legal status
  • US: ℞-only
Identifiers
CAS Number
ChemSpider
  • none
 ☒NcheckY (what is this?)  

Estradiol/norethisterone acetate (E2/NETA), sold under the brand name Activella among others, is a combination of estradiol (E2) and norethisterone acetate (NETA) which is used in the treatment of vasomotor symptoms, vulvar and vaginal atrophy, and osteoporosis[1] associated with menopause.[2] Activella specifically is marketed by Novo Nordisk and is supplied as film-coated tablets containing 1 mg estradiol and 0.5 mg norethisterone acetate. CombiPatch is a combination of estradiol and NETA provided as a transdermal patch.[2]

See also[]

  • Ethinylestradiol/norethisterone acetate
  • Ethinylestradiol/norelgestromin
  • Estradiol/levonorgestrel
  • List of combined sex-hormonal preparations

References[]

  1. ^ Morabito N, Crisafulli A, Vergara C, Gaudio A, Lasco A, Frisina N, et al. (October 2002). "Effects of genistein and hormone-replacement therapy on bone loss in early postmenopausal women: a randomized double-blind placebo-controlled study". Journal of Bone and Mineral Research. 17 (10): 1904–12. doi:10.1359/jbmr.2002.17.10.1904. PMID 12369794. S2CID 29312298.
  2. ^ a b "CombiPatch (estradiol/norethindrone acetate transdermal system) Prescribing Information" (PDF). Noven Pharmaceuticals, Inc. U.S Food and Drug Administration.
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