Hydramethylnon

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Hydramethylnon
Hydramethylnon.png
Names
IUPAC name
2(1H-4,4-dimethyl tetrahydro pyrimidinylidene )

(3-(4-(trifluoromethyl)phenyl) -1-(2-(4-(trifluoromethyl)phenyl)ethenyl)

-2-propenylidene)hydrazone
Identifiers
  • 67485-29-4 checkY
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.100.669 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C25H24F6N4/c1-23(2)15-32-22(33-16-23)35-34-21(13-7-17-3-9-19(10-4-17)24(26,27)28)14-8-18-5-11-20(12-6-18)25(29,30)31/h3-14H,15-16H2,1-2H3,(H2,32,33,35)/b13-7+,14-8+ checkY
    Key: IQVNEKKDSLOHHK-FNCQTZNRSA-N checkY
  • InChI=1/C25H24F6N4/c1-23(2)15-32-22(33-16-23)35-34-21(13-7-17-3-9-19(10-4-17)24(26,27)28)14-8-18-5-11-20(12-6-18)25(29,30)31/h3-14H,15-16H2,1-2H3,(H2,32,33,35)/b13-7+,14-8+
    Key: IQVNEKKDSLOHHK-FNCQTZNRBM
  • FC(F)(F)c1ccc(cc1)C=CC(=NNC2=NCC(C)(C)CN2)C=Cc3ccc(cc3)C(F)(F)F
Properties
C25H24F6N4
Molar mass 494.485 g·mol−1
Appearance Yellow to orange crystalline solid
Melting point 185 to 190 °C (365 to 374 °F; 458 to 463 K)
Hazards
NFPA 704 (fire diamond)
1
1
0
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY  (what is checkY☒N ?)
Infobox references

Hydramethylnon is an organic chemical compound. It is also known as AC 217,300. It is in a chemical class called trifluoromethyl aminohydrazone, which is a . It is classified as a pesticide designed to control insects that are harmful to humans.[1] It works by inhibiting complex III in the mitochondrial inner membrane and leads to a halting of oxidative phosphorylation. It is used primarily as an insecticide in the form of baits for cockroaches and ants.[2] Some brands of insecticides that include hydramethylnon are Amdro, Combat, Blatex, Cyaforce, Cyclon, Faslane, Grant's, Impact, Matox, Maxforce, Pyramdron, Siege, Scuttle and Wipeout. Hydramethylnon is a slow-acting poison with delayed toxicity that needs to be eaten to be effective.[3]

Toxicology[]

Hydramethylnon has low toxicity to mammals.[2][3] The oral LD50 is 1100–1300 mg/kg in rats and above 28,000 mg/kg in dogs.[3] Hydramethylnon is toxic to fish; the 96-hour LC50 in rainbow trout is 0.16 mg/L, 0.10 mg/L in channel catfish, and 1.70 mg/L in bluegill sunfish.

Hydramethylnon, when fed to rats for two years led to an increase in uterine and adrenal tumors at the highest dose; therefore, the Environmental Protection Agency classifies hydramethylnon as a possible human carcinogen.[3]

See also[]

  • Fipronil, another insecticide used for similar purposes

References[]

  1. ^ "Hydramethylnon". PubChem.
  2. ^ a b Veterinary Support Personnel Network
  3. ^ a b c d "Hydramethylnon" (PDF). National Pesticide Information Center.

External links[]

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