Sarolaner
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Trade names | Simparica |
Other names | PF-6450567 |
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ECHA InfoCard | 100.234.000 |
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Formula | C23H18Cl2F4N2O5S |
Molar mass | 581.36 g·mol−1 |
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Sarolaner (brand name Simparica) is an ectoparasiticide veterinary drug for the treatment of flea and tick infestations in dogs.[1][2] It is also used off-label to control sarcoptic mange and demodectic mange.[2]
Sarolaner is also a component of the combination drug Simparica Trio, which contains sarolaner, moxidectin, and pyrantel. It is used for prevention of heartworm disease caused by Dirofilaria immitis; treat and prevent flea infestations; treat and control tick infestations with the lone star tick, Gulf Coast tick, American dog tick, black-legged tick, and brown dog tick; and treat and control roundworm and adult hookworm infections.[3]
References[]
- ^ McTier TL, Chubb N, Curtis MP, Hedges L, Inskeep GA, Knauer CS, et al. (May 2016). "Discovery of sarolaner: A novel, orally administered, broad-spectrum, isoxazoline ectoparasiticide for dogs". Veterinary Parasitology. 222: 3–11. doi:10.1016/j.vetpar.2016.02.019. PMID 26961590.
- ^ a b Gollakner R. "Sarolaner". vcahospitals.com. VCA Hospitals. Retrieved June 26, 2021.
- ^ "FDA Approves Simparica Trio, a Combination Drug for Heartworm and Other Parasites". Food and Drug Administration. March 2, 2020. Retrieved June 26, 2021.
Categories:
- Drugs not assigned an ATC code
- Veterinary drugs
- Insecticides
- Acaricides
- Spiro compounds
- Azetidines
- Trifluoromethyl compounds
- Chloroarenes
- Fluoroarenes
- Isoxazolines
- Sulfones
- Antiinfective agent stubs