S-formylglutathione hydrolase
| S-formylglutathione hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.2.12 | ||||||||
| CAS no. | 50812-21-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a S-formylglutathione hydrolase (EC 3.1.2.12) is an enzyme that catalyzes the chemical reaction
- S-formylglutathione + H2O glutathione + formate
Thus, the two substrates of this enzyme are and H2O, whereas its two products are glutathione and formate.
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is S-formylglutathione hydrolase. This enzyme participates in .
References[]
- Uotila L (1973). "Preparation and assay of glutathione people will diethiol esters. Survey of human liver glutathione thiol esterases". Biochemistry. 12 (20): 3938–43. doi:10.1021/bi00744a024. PMID 4200890.
- Uotila L, Koivusalo M (1974). "Purification and properties of S-formylglutathione hydrolase from human liver". J. Biol. Chem. 249 (23): 7664–72. PMID 4436331.
- Harms N, Ras J, Reijnders WN, van Spanning RJ, Stouthamer AH (1996). "S-formylglutathione hydrolase of Paracoccus denitrificans is homologous to human esterase D: a universal pathway for formaldehyde detoxification?". J. Bacteriol. 178 (21): 6296–9. PMC 178503. PMID 8892832.
Categories:
- EC 3.1.2
- Enzymes of unknown structure
- EC 3.1 stubs