SoRI-9804
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Names | |
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Preferred IUPAC name
N-(Diphenylmethyl)-2-phenylquinazolin-4-amine | |
Other names
Benzhydryl-(2-phenyl-quinazolin-4-yl)-amine; 4-((Diphenylmethyl)amino)-2-phenylquinazoline
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Identifiers | |
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3D model (JSmol)
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ChEMBL | |
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PubChem CID
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Properties | |
Chemical formula
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C27H21N3 |
Molar mass | 387.486 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
SoRI-9804 is a positive allosteric modulator of dopamine transporters. Unlike others in its series & traditional DRI ligands, it inhibits the release of dopamine in addition to inhibiting the reuptake of released dopamine back into the transporter.[1]
See also[]
References[]
- ^ Rothman, Richard B.; Dersch, Christina M.; Ananthan, Subramaniam; Partilla, John S. (May 2009). "Studies of the biogenic amine transporters. 13. Identification of "agonist" and "antagonist" allosteric modulators of amphetamine-induced dopamine release". Journal of Pharmacology and Experimental Therapeutics. 329 (2): 718–28. doi:10.1124/jpet.108.149088. PMC 2672863. PMID 19244097.
Categories:
- Quinazolines
- Organic compound stubs