From Wikipedia, the free encyclopedia
Benmoxin Routes of administration Oral ATC code Legal status
In general: ℞ (Prescription only)
N' -(1-phenylethyl)benzohydrazide
CAS Number PubChem CID ChemSpider UNII ChEMBL CompTox Dashboard (EPA ) ECHA InfoCard 100.028.745 Formula C 15 H 16 N 2 O Molar mass 240.306 g·mol−1 3D model (JSmol )
O=C(NNC(c1ccccc1)C)c2ccccc2
InChI=1S/C15H16N2O/c1-12(13-8-4-2-5-9-13)16-17-15(18)14-10-6-3-7-11-14/h2-12,16H,1H3,(H,17,18)
Y Key:BEWNZPMDJIGBED-UHFFFAOYSA-N
Y
N Y (what is this?)
Benmoxin (trade names Neuralex , Nerusil ), also known as mebamoxine , is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine class.[1] [2] It was synthesized in 1967 and was subsequently used as an antidepressant in Europe , but is now no longer marketed.[1] [2]
See also [ ]
References [ ]
Antidepressants (N06A )
SSRIs SNRIs NRIs NDRIs
Amineptine ‡
Bupropion
Nomifensine ‡
NaSSAs SARIs SMS Others
Monoamine oxidase inhibitors
Non-selective MAOA -selectiveMAOB -selective
# WHO-EM
‡ Withdrawn from market
Clinical trials :
† Phase III
§ Never to phase III
Non-specific
AAAD
Substrates→Products: L -DOPA (levodopa) →Dopamine
5-HTP →Serotonin
L -Histidine →Histamine
Phenylalanine →Phenethylamine
L -Tyrosine →Tyramine
Tryptophan →Tryptamine
MAO
Phenethylamines (dopamine , epinephrine ,norepinephrine )
PAH
Substrates→Products: Phenylalanine →Tyrosine
TH DBH
Substrates→Products: Dopamine →Norepinephrine (Noradrenaline)
PNMT
Substrates→Products: Norepinephrine (noradrenaline) →Epinephrine (adrenaline)
COMT
Tryptamines (serotonin , melatonin )
TPH
Substrates→Products: Tryptophan →5-HTP
AANAT ASMT
Histamine
HDC
Substrates→Products: L -Histidine →Histamine
HNMT
Substrates→Products: Histamine →
DAO
Substrates→Products: Histamine →
See also: Receptor/signaling modulators • Adrenergics • Dopaminergics • Melatonergics • Serotonergics • Monoamine reuptake inhibitors • Monoamine releasing agents • Monoamine neurotoxins
Categories :
Drugs not assigned an ATC code Abandoned drugs Benzamides Hydrazides Monoamine oxidase inhibitors Nervous system drug stubs Hidden categories:
Drugs with non-standard legal status Articles with changed CASNo identifier Articles with changed EBI identifier ECHA InfoCard ID from Wikidata Chemical pages without DrugBank identifier Articles without KEGG source Drugboxes which contain changes to verified fields Drugboxes which contain changes to watched fields All stub articles