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α-Difluoromethyl-DOPA
Names
Preferred IUPAC name
(2S )-2-Amino-2-[(3,4-dihydroxyphenyl)methyl]-3,3-difluoropropanoic acid
Identifiers
CAS Number
3D model (JSmol )
ChemSpider
MeSH
alpha-difluoromethyl-DOPA
UNII
InChI=1S/C10H11F2NO4/c11-8(12)10(13,9(16)17)4-5-1-2-6(14)7(15)3-5/h1-3,8,14-15H,4,13H2,(H,16,17)/t10-/m1/s1
Y Key: XZVHHLNLLVICFA-SNVBAGLBSA-N
Y InChI=1/C10H11F2NO4/c11-8(12)10(13,9(16)17)4-5-1-2-6(14)7(15)3-5/h1-3,8,14-15H,4,13H2,(H,16,17)/t10-/m1/s1
Key: XZVHHLNLLVICFA-SNVBAGLBBM
C1=CC(=C(C=C1C[C@@](C(F)F)(C(=O)O)N)O)O
FC(F)[C@](C(=O)O)(N)Cc1cc(O)c(O)cc1
Properties
Chemical formula
C10 H11 F2 NO4
Molar mass
247.20 g/mol
Density
1.528 g/mL
Boiling point
479 °C (894 °F; 752 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N (what is Y N ?)
Infobox references
Chemical compound
α-Difluoromethyl-DOPA (DFMD , DFM-DOPA ) is a DOPA decarboxylase inhibitor .[1]
See also [ ]
References [ ]
Non-specific
AAAD
Substrates→Products: L -DOPA (levodopa) →Dopamine
5-HTP →Serotonin
L -Histidine →Histamine
Phenylalanine →Phenethylamine
L -Tyrosine →Tyramine
Tryptophan →Tryptamine
MAO
Substrates→Products (with ALDH /ALR ): Epinephrine (adrenaline) →DHMA
Metanephrine →MHPG /VMA
Norepinephrine (noradrenaline) →DHMA
Normetanephrine →MHPG /VMA
Dopamine →DOPAC
3-Methoxytyramine →HVA
Serotonin →5-HIAA
Phenethylamines (dopamine , epinephrine ,norepinephrine )
PAH
Substrates→Products: Phenylalanine →Tyrosine
Inhibitors: 3,4-Dihydroxystyrene
TH
Substrates→Products: Tyrosine →L -DOPA (levodopa)
Inhibitors: 2-Hydroxyestradiol
2-Hydroxyestrone
3-Iodotyrosine
Aquayamycin
Bulbocapnine
Metirosine
Oudenone
DBH
Substrates→Products: Dopamine →Norepinephrine (Noradrenaline)
Inhibitors: Bupicomide
Disulfiram
Dopastin
Fusaric acid
Nepicastat
Phenopicolinic acid
Tropolone
PNMT
Substrates→Products: Norepinephrine (noradrenaline) →Epinephrine (adrenaline)
COMT
Substrates→Products: Dopamine →3-Methoxytyramine
DOPAC →Homovanillic acid
Norepinephrine →Normetanephrine
Epinephrine →Metanephrine
DOPEG →MOPEG
DOMA →VMA
2-Hydroxyestradiol →2-Methoxyestradiol
2-Hydroxyestrone →2-Methoxyestrone
4-Hydroxyestradiol →4-Methoxyestradiol
4-Hydroxyestrone →4-Methoxyestrone
Tryptamines (serotonin , melatonin )
TPH
Substrates→Products: Tryptophan →5-HTP
AANAT
Substrates→Products: Serotonin →N-Acetylserotonin
ASMT
Substrates→Products: N-Acetylserotonin →Melatonin
Histamine
HDC
Substrates→Products: L -Histidine →Histamine
Inhibitors: Catechin
Alpha-Fluoromethylhistidine
Histidine methyl ester
Meciadanol
Naringenin
Tritoqualine
HNMT
Substrates→Products: Histamine →
DAO
Substrates→Products: Histamine →
Inhibitors: Pimagedine (aminoguanidine)
See also: Receptor/signaling modulators • Adrenergics • Dopaminergics • Melatonergics • Serotonergics • Monoamine reuptake inhibitors • Monoamine releasing agents • Monoamine neurotoxins
Phenethylamines
Phenethylamines
Psychedelics: 25B-NBOMe
25C-NBOMe
25D-NBOMe
25I-NBOMe
25N-NBOMe
2C-B
2C-C
2C-CP
2C-D
2C-E
2C-EF
2C-F
2C-G
2C-G-1
2C-G-2
2C-G-3
2C-G-4
2C-G-5
2C-G-6
2C-G-N
2C-H
2C-I
2C-iP
2C-N
2C-O
2C-O-4
2C-P
2C-SE
2C-T
2C-T-2
2C-T-3
2C-T-4
2C-T-7
2C-T-8
2C-T-9
2C-T-13
2C-T-15
2C-T-16
2C-T-17
2C-T-19
2C-T-21
2C-T-28
2C-TFE
2C-TFM
2C-YN
2C-V
Allylescaline
DESOXY
Escaline
Isoproscaline
Jimscaline
Macromerine
MEPEA
Mescaline
Metaescaline
Methallylescaline
Proscaline
Psi-2C-T-4
TCB-2
Stimulants: Phenylethanolamine
Hordenine
Phenethylamine
Phenpromethamine
α-Methylphenethylamine (amphetamine)
β-Methylphenethylamine
m -Methylphenethylamine
N -Methylphenethylamine
o -Methylphenethylamine
p -Methylphenethylamine
Methylphenidate
Amphetamines Phentermines Cathinones Phenylisobutylamines
Entactogens: 4-CAB
4-MAB
Ariadne
BDB
Butylone
EBDB
Eutylone
MBDB Stimulants: Phenylisobutylamine
Phenylalkylpyrrolidines Catecholamines (and close relatives) Miscellaneous
Categories :
Aromatic L-amino acid decarboxylase inhibitors Amino acids Catecholamines Organofluorides Hidden categories:
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