Echinopsidine

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Echinopsidine
Skeletal formula of echinopsidine
Clinical data
Other namesEchinopsidine Iodide
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 1-Methyl-2,3-dihydroquinolin-4-imine
CAS Number
  • 2400-75-1
    58916-73-7 (hydroiodide)
PubChem CID
ChemSpider
Chemical and physical data
FormulaC10H12N2
Molar mass160.220 g·mol−1

Echinopsidine (Adepren) is an antidepressant that was under development in Bulgaria for the treatment of depression.[1][2] It increases serotonin, norepinephrine, and dopamine levels in the brain and is believed to act as a monoamine oxidase inhibitor (MAOI).[3][4][5] Echinopsidine is found naturally in Echinops echinatus along with the related alkaloids and .[6]

See also[]

  • Monoamine oxidase inhibitor

References[]

  1. ^ Guliamov MG (1982). "[Experience with the use of new Bulgarian psychotropic drugs]". Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952) (in Russian). 82 (11): 115–22. PMID 6758442.
  2. ^ Guliamov MG (1986). "[Comparative evaluation of the therapeutic efficacy of the antidepressants adepren, linamiphen and emovit]". Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952) (in Russian). 86 (4): 582–7. PMID 3716711.
  3. ^ Tiutiulkova N; Gorancheva Iu (1978). "[Effect of adepren on the cerebral concentration of serotonin]". Eksperimentalna Meditsina I Morfologiia (in Bulgarian). 17 (2): 83–5. PMID 658004.
  4. ^ Stefanova D, Tiutiulkova N, Nikolova M (1976). "[Effect of adepren on the behavior and brain catecholamines of rats in an open field setup]". Eksperimentalna Meditsina I Morfologiia (in Bulgarian). 15 (1): 42–6. PMID 1269462.
  5. ^ Tiutiulkova NI; Gorancheva IuI (1975). "[Excretion of dopamine, noradrenaline, adrenaline, vanilmandelic acid and 5-hydroxyindoleacetic acid in the urine of volunteers treated with adepren]". Eksperimentalna Meditsina I Morfologiia (in Bulgarian). 14 (4): 187–9. PMID 1222713.
  6. ^ Indian Medicinal Plants An Illustrated Dictionary. Springer-Verlag Berlin Heidelberg. 2007. ISBN 978-0-387-70637-5.
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