Not to be confused with Sepazon or Sibazon , a brand name for diazepam in Russia).
Cloxazolam Trade names Akton, Cloxam, Clozal, Elum, Olcadil, and Sepazon[1] AHFS /Drugs.com International Drug Names Routes of Oral ATC code Legal status
CA Schedule IV DE Anlage III (Special prescription form required) UK :Class C US :Schedule IV
Metabolism Hepatic Elimination half-life 65 hours Excretion Renal
10-chloro-11b -(2-chlorophenyl)-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d ][1,4]benzodiazepin-6-one
CAS Number PubChem CID DrugBank ChemSpider UNII KEGG ChEMBL CompTox Dashboard (EPA ) Formula C 17 H 14 Cl 2 N 2 O 2 Molar mass −1 3D model (JSmol )
Clc1ccccc1C42OCCN2CC(=O)Nc3c4cc(Cl)cc3
InChI=1S/C17H14Cl2N2O2/c18-11-5-6-15-13(9-11)17(12-3-1-2-4-14(12)19)21(7-8-23-17)10-16(22)20-15/h1-6,9H,7-8,10H2,(H,20,22)
Y Key:ZIXNZOBDFKSQTC-UHFFFAOYSA-N
Y N Y (what is this?)
Cloxazolam is a benzodiazepine derivative that has anxiolytic , sedative , and anticonvulsant properties.
[2] [2] [1] [3]
See also [ ] References [ ]
^ a b "Cloxazolam International Brands" . Drugs.com. Retrieved 13 August 2018 .^ a b Stolerman IP, ed. (2010). "C: Cloxazolam". Encyclopedia of Psychopharmacology . Berlin: Springer-Verlag. ISBN 978-3-540-68706-1 ^ "Bon à savoir" . cbip.be. Retrieved 13 August 2018 .
External links [ ]
Anxiolytics (N05B )
5-HT1A R agonists GABAA R PAMs
Benzodiazepines :Adinazolam Alprazolam Bromazepam Camazepam Chlordiazepoxide Clobazam Clonazepam Clorazepate Clotiazepam Cloxazolam Diazepam # Ethyl loflazepate Etizolam Fludiazepam Halazepam Ketazolam Lorazepam # Medazepam Nordazepam Oxazepam Pinazepam Prazepam ; Others: Alpidem ‡ Barbiturates (e.g., phenobarbital )Carisoprodol Carbamates (e.g., meprobamate )Chlormezanone ‡ Ethanol (alcohol) Etifoxine Imepitoin ; Herbs: Kava Skullcap Valerian Gabapentinoids (α2 δ VDCC blockers )
Gabapentin Gabapentin enacarbil Phenibut Pregabalin Antidepressants
SSRIs escitalopram )SNRIs duloxetine )SARIs trazodone )TCAs clomipramine # )TeCAs mirtazapine )MAOIs phenelzine ); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics )
Alpha-1 blockers (e.g., prazosin )Alpha-2 agonists (e.g., clonidine , dexmedetomidine , guanfacine )Beta blockers (e.g., propranolol ) Others
Benzoctamine Cannabidiol Cycloserine Fabomotizole Hydroxyzine Kanna Lavender Lorpiprazole Mebicar Mepiprazole Nicotine Opipramol Oxaflozane ‡ Phenaglycodol Phenibut Picamilon Selank Tiagabine Tofisopam Validolum
# WHO-EM ‡ Withdrawn from marketClinical trials :
† Phase III § Never to phase III
Benzodiazepines
1,4-Benzodiazepines 1,5-Benzodiazepines 2,3-Benzodiazepines* Triazolobenzodiazepines Imidazobenzodiazepines
Bretazenil Climazolam EVT-201 FG-8205 Flumazenil GL-II-73 Imidazenil 123 I-IomazenilL-655,708 Loprazolam Midazolam PWZ-029 Remimazolam Ro15-4513 Ro48-6791 Ro48-8684 Ro4938581 Sarmazenil SH-053-R-CH3-2′F Oxazolobenzodiazepines Thienodiazepines Thienotriazolodiazepines Thienobenzodiazepines *Pyridodiazepines Pyridotriazolodiazepines Pyrazolodiazepines Pyrrolodiazepines Tetrahydroisoquinobenzodiazepines Pyrrolobenzodiazepines *Benzodiazepine prodrugs * atypical activity profile (not GABAA receptor ligands)
GABA A receptor positive modulatorsAlcohols
Butanol Chloralodol Chlorobutanol (cloretone) Ethanol (alcohol) (alcoholic drink )Ethchlorvynol Isobutanol Isopropanol Menthol Methanol Methylpentynol Pentanol Petrichloral Propanol tert -Butanol (2M2P)tert -Pentanol (2M2B)Tribromoethanol Trichloroethanol Triclofos Trifluoroethanol Barbiturates Benzodiazepines Carbamates Flavonoids
Ampelopsin (dihydromyricetin) Apigenin Baicalein Baicalin Catechin EGC EGCG Hispidulin Luteolin Skullcap constituents (e.g., baicalin )Wogonin Imidazoles Kava constituents
Desmethoxyyangonin Kavain Methysticin Yangonin Monoureides Neuroactive steroids Nonbenzodiazepines Phenols
Fospropofol Propofol Thymol Piperidinediones Pyrazolopyridines Quinazolinones Volatiles /gases
Acetone Acetophenone Acetylglycinamide chloral hydrate Aliflurane Benzene Butane Butylene Centalun Chloral Chloral betaine Chloral hydrate Chloroform Cryofluorane Desflurane Dichloralphenazone Dichloromethane Diethyl ether Enflurane Ethyl chloride Ethylene Fluroxene Gasoline Halopropane Halothane Isoflurane Kerosine Methoxyflurane Methoxypropane Nitric oxide Nitrogen Nitrous oxide Norflurane Paraldehyde Propane Propylene Roflurane Sevoflurane Synthane Teflurane Toluene Trichloroethane (methyl chloroform) Trichloroethylene Vinyl ether Others/unsorted
3-Hydroxybutanal Avermectins (e.g., ivermectin )Bromide compounds (e.g., lithium bromide , potassium bromide , sodium bromide )Carbamazepine Chloralose Chlormezanone Clomethiazole DEABL Dihydroergolines (e.g., dihydroergocryptine , , dihydroergotamine , ergoloid (dihydroergotoxine) )Efavirenz Etazepine Etifoxine Fenamates (e.g., flufenamic acid , mefenamic acid , niflumic acid , tolfenamic acid )Fluoxetine Flupirtine Hopantenic acid Lanthanum Lavender oil Lignans (e.g., 4-O-methylhonokiol , honokiol , magnolol , obovatol )Loreclezole Menthyl isovalerate (validolum) Monastrol Niacin Niacinamide Org 25,435 Phenytoin Propanidid Retigabine (ezogabine) Safranal Seproxetine Stiripentol (e.g., sulfonmethane (sulfonal) , tetronal , trional )
Terpenoids (e.g., borneol )Topiramate Valerian constituents (e.g., isovaleric acid , isovaleramide , valerenic acid , )Unsorted benzodiazepine site positive modulators: α-Pinene See also: Receptor/signaling modulators • GABA receptor modulators • GABA metabolism/transport modulators
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