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Hydroxyphenamate Trade names Listica
(2-hydroxy-2-phenylbutyl) carbamate
CAS Number PubChem CID ChemSpider UNII KEGG ChEBI ChEMBL ECHA InfoCard 100.000.016 Formula C 11 H 15 N O 3 Molar mass −1 3D model (JSmol )
CCC(COC(=O)N)(C1=CC=CC=C1)O
InChI=1S/C11H15NO3/c1-2-11(14,8-15-10(12)13)9-6-4-3-5-7-9/h3-7,14H,2,8H2,1H3,(H2,12,13)
Key:WAFIYOULDIWAKR-UHFFFAOYSA-N
Hydroxyphenamate or oxyfenamate (trade name Listica ) is a sedative and anxiolytic drug of the carbamate class which is no longer marketed in the US. Like other carbamate sedatives, it is chemically related to meprobamate (Miltown). It was introduced to the US market in 1961. The dosage for adults is 200 mg 3 to 4 times daily.[1]
References [ ]
^ American Medical Association Dept of Drugs (1977). AMA Drug Evaluations (3rd ed.). Littleton, Mass.: Pub. Sciences Group. p. N-61. ISBN 978-0-88416-175-2 OCLC 1024170745 .
Anxiolytics (N05B )
5-HT1A R agonists GABAA R PAMs
Benzodiazepines :Adinazolam Alprazolam Bromazepam Camazepam Chlordiazepoxide Clobazam Clonazepam Clorazepate Clotiazepam Cloxazolam Diazepam # Ethyl loflazepate Etizolam Fludiazepam Halazepam Ketazolam Lorazepam # Medazepam Nordazepam Oxazepam Pinazepam Prazepam ; Others: Alpidem ‡ Barbiturates (e.g., phenobarbital )Carisoprodol Carbamates (e.g., meprobamate )Chlormezanone ‡ Ethanol (alcohol) Etifoxine Imepitoin ; Herbs: Kava Skullcap Valerian Gabapentinoids (α2 δ VDCC blockers )
Gabapentin Gabapentin enacarbil Phenibut Pregabalin Antidepressants
SSRIs escitalopram )SNRIs duloxetine )SARIs trazodone )TCAs clomipramine # )TeCAs mirtazapine )MAOIs phenelzine ); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics )
Alpha-1 blockers (e.g., prazosin )Alpha-2 agonists (e.g., clonidine , dexmedetomidine , guanfacine )Beta blockers (e.g., propranolol ) Others
Benzoctamine Cannabidiol Cycloserine Fabomotizole Hydroxyzine Kanna Lavender Lorpiprazole Mebicar Mepiprazole Nicotine Opipramol Oxaflozane ‡ Phenaglycodol Phenibut Picamilon Selank Tiagabine Tofisopam Validolum
# WHO-EM ‡ Withdrawn from marketClinical trials :
† Phase III § Never to phase III
GABA A receptor positive modulatorsAlcohols
Butanol Chloralodol Chlorobutanol (cloretone) Ethanol (alcohol) (alcoholic drink )Ethchlorvynol Isobutanol Isopropanol Menthol Methanol Methylpentynol Pentanol Petrichloral Propanol tert -Butanol (2M2P)tert -Pentanol (2M2B)Tribromoethanol Trichloroethanol Triclofos Trifluoroethanol Barbiturates Benzodiazepines Carbamates Flavonoids
Ampelopsin (dihydromyricetin) Apigenin Baicalein Baicalin Catechin EGC EGCG Hispidulin Luteolin Skullcap constituents (e.g., baicalin )Wogonin Imidazoles Kava constituents
Desmethoxyyangonin Kavain Methysticin Yangonin Monoureides Neuroactive steroids Nonbenzodiazepines Phenols
Fospropofol Propofol Thymol Piperidinediones Pyrazolopyridines Quinazolinones Volatiles /gases
Acetone Acetophenone Acetylglycinamide chloral hydrate Aliflurane Benzene Butane Butylene Centalun Chloral Chloral betaine Chloral hydrate Chloroform Cryofluorane Desflurane Dichloralphenazone Dichloromethane Diethyl ether Enflurane Ethyl chloride Ethylene Fluroxene Gasoline Halopropane Halothane Isoflurane Kerosine Methoxyflurane Methoxypropane Nitric oxide Nitrogen Nitrous oxide Norflurane Paraldehyde Propane Propylene Roflurane Sevoflurane Synthane Teflurane Toluene Trichloroethane (methyl chloroform) Trichloroethylene Vinyl ether Others/unsorted
3-Hydroxybutanal Avermectins (e.g., ivermectin )Bromide compounds (e.g., lithium bromide , potassium bromide , sodium bromide )Carbamazepine Chloralose Chlormezanone Clomethiazole DEABL Dihydroergolines (e.g., dihydroergocryptine , , dihydroergotamine , ergoloid (dihydroergotoxine) )Efavirenz Etazepine Etifoxine Fenamates (e.g., flufenamic acid , mefenamic acid , niflumic acid , tolfenamic acid )Fluoxetine Flupirtine Hopantenic acid Lanthanum Lavender oil Lignans (e.g., 4-O-methylhonokiol , honokiol , magnolol , obovatol )Loreclezole Menthyl isovalerate (validolum) Monastrol Niacin Niacinamide Org 25,435 Phenytoin Propanidid Retigabine (ezogabine) Safranal Seproxetine Stiripentol (e.g., sulfonmethane (sulfonal) , tetronal , trional )
Terpenoids (e.g., borneol )Topiramate Valerian constituents (e.g., isovaleric acid , isovaleramide , valerenic acid , )Unsorted benzodiazepine site positive modulators: α-Pinene See also: Receptor/signaling modulators • GABA receptor modulators • GABA metabolism/transport modulators
Categories :
Anxiolytics Carbamates GABAA receptor positive allosteric modulators Tertiary alcohols Hidden categories:
ECHA InfoCard ID from Wikidata Chemical pages without DrugBank identifier Drugs missing an ATC code Drugs with no legal status Articles containing unverified chemical infoboxes
