para -MethoxyethylamphetamineLegal status
DE : Anlage II (Authorized trade only, not prescriptible)
UK : Class A
N -ethyl-1-(4-methoxyphenyl)propan-2-amine
CAS Number PubChem CID ChemSpider UNII CompTox Dashboard (EPA ) ECHA InfoCard 100.034.839 Formula C 12 H 19 N O Molar mass 193.290 g·mol−1 3D model (JSmol )
InChI=1S/C12H19NO/c1-4-13-10(2)9-11-5-7-12(14-3)8-6-11/h5-8,10,13H,4,9H2,1-3H3
Key:USBWBBAUWVUJLA-UHFFFAOYSA-N
para -Methoxy ethyl amphetamine (PMEA ), is a stimulant drug related to PMA . PMEA reputedly produces similar effects to PMA, but is considerably less potent[1] and seems to have slightly less tendency to produce severe hyperthermia , at least at low doses. At higher doses however the side effects and danger of death approach those of PMA itself, and PMEA should still be considered a potentially dangerous drug. Investigation of a drug-related death in Japan in 2005 showed PMEA to be present in the body and was thought to be responsible for the death.[2]
See also [ ]
References [ ]
^ Bustamante D, Díaz-Véliz G, Paeile C, Zapata-Torres G, Cassels BK (October 2004). "Analgesic and behavioral effects of amphetamine enantiomers, p-methoxyamphetamine and n-alkyl-p-methoxyamphetamine derivatives". Pharmacology, Biochemistry, and Behavior . 79 (2): 199–212. doi :10.1016/j.pbb.2004.06.017 . PMID 15501295 .
^ Zaitsu K, Katagi M, Kamata T, Kamata H, Shima N, Tsuchihashi H, et al. (May 2008). "Determination of a newly encountered designer drug "p-methoxyethylamphetamine" and its metabolites in human urine and blood". Forensic Science International . 177 (1): 77–84. doi :10.1016/j.forsciint.2007.11.001 . PMID 18155375 .
DRAs
Piperazines: 2C-B-BZP
BZP
MBZP
MDBZP
MeOPP
oMPP
NRAs
Piperazines: 2C-B-BZP
BZP
MBZP
mCPP
MDBZP
MeOPP
oMPP
pFPP
SRAs
Piperazines: 2C-B-BZP
BZP
MBZP
mCPP
MDBZP
MeOPP
Mepiprazole
oMPP
pCPP
pFPP
pTFMPP
TFMPP
Tryptamines: 4-Methyl-αET
4-Methyl-αMT
5-CT
5-MeO-αET
5-MeO-αMT
5-MT
αET
αMT
DMT
Tryptamine
Others
DAT modulators: Agonist-like: SoRI-9804
; Antagonist-like: SoRI-20041
See also: Receptor/signaling modulators • Monoamine reuptake inhibitors • Adrenergics • Dopaminergics • Serotonergics • Monoamine metabolism modulators • Monoamine neurotoxins
Non-specific
AAAD
Substrates→Products: L -DOPA (levodopa) →Dopamine
5-HTP →Serotonin
L -Histidine →Histamine
Phenylalanine →Phenethylamine
L -Tyrosine →Tyramine
Tryptophan →Tryptamine
Inhibitors: Benserazide
Carbidopa
DFMD
Genistein
Methyldopa
MAO
Substrates→Products (with ALDH /ALR ): Epinephrine (adrenaline) →DHMA
Metanephrine →MHPG /VMA
Norepinephrine (noradrenaline) →DHMA
Normetanephrine →MHPG /VMA
Dopamine →DOPAC
3-Methoxytyramine →HVA
Serotonin →5-HIAA
Phenethylamines (dopamine , epinephrine ,norepinephrine )
PAH
Substrates→Products: Phenylalanine →Tyrosine
Inhibitors: 3,4-Dihydroxystyrene
TH
Substrates→Products: Tyrosine →L -DOPA (levodopa)
Inhibitors: 2-Hydroxyestradiol
2-Hydroxyestrone
3-Iodotyrosine
Aquayamycin
Bulbocapnine
Metirosine
Oudenone
DBH
Substrates→Products: Dopamine →Norepinephrine (Noradrenaline)
Inhibitors: Bupicomide
Disulfiram
Dopastin
Fusaric acid
Nepicastat
Phenopicolinic acid
Tropolone
PNMT
Substrates→Products: Norepinephrine (noradrenaline) →Epinephrine (adrenaline)
COMT
Substrates→Products: Dopamine →3-Methoxytyramine
DOPAC →Homovanillic acid
Norepinephrine →Normetanephrine
Epinephrine →Metanephrine
DOPEG →MOPEG
DOMA →VMA
2-Hydroxyestradiol →2-Methoxyestradiol
2-Hydroxyestrone →2-Methoxyestrone
4-Hydroxyestradiol →4-Methoxyestradiol
4-Hydroxyestrone →4-Methoxyestrone
Inhibitors: 2-Hydroxyestradiol
2-Hydroxyestrone
Entacapone
Nitecapone
Opicapone
Quinalizarin
Tolcapone
Tryptamines (serotonin , melatonin )
TPH
Substrates→Products: Tryptophan →5-HTP
AANAT
Substrates→Products: Serotonin →N-Acetylserotonin
ASMT
Substrates→Products: N-Acetylserotonin →Melatonin
Histamine
HDC
Substrates→Products: L -Histidine →Histamine
Inhibitors: Catechin
Alpha-Fluoromethylhistidine
Histidine methyl ester
Meciadanol
Naringenin
Tritoqualine
HNMT
Substrates→Products: Histamine →
Inhibitors: Amodiaquine
Diphenhydramine
Harmaline
Quinacrine
SKF-91488
Tacrine
DAO
Substrates→Products: Histamine →
Inhibitors: Pimagedine (aminoguanidine)
See also: Receptor/signaling modulators • Adrenergics • Dopaminergics • Melatonergics • Serotonergics • Monoamine reuptake inhibitors • Monoamine releasing agents • Monoamine neurotoxins
Phenethylamines
Phenethylamines
Psychedelics: 25B-NBOMe
25C-NBOMe
25D-NBOMe
25I-NBOMe
25N-NBOMe
2C-B
2C-C
2C-CP
2C-D
2C-E
2C-EF
2C-F
2C-G
2C-G-1
2C-G-2
2C-G-3
2C-G-4
2C-G-5
2C-G-6
2C-G-N
2C-H
2C-I
2C-iP
2C-N
2C-O
2C-O-4
2C-P
2C-SE
2C-T
2C-T-2
2C-T-3
2C-T-4
2C-T-7
2C-T-8
2C-T-9
2C-T-13
2C-T-15
2C-T-16
2C-T-17
2C-T-19
2C-T-21
2C-T-28
2C-TFE
2C-TFM
2C-YN
2C-V
Allylescaline
DESOXY
Escaline
Isoproscaline
Jimscaline
Macromerine
MEPEA
Mescaline
Metaescaline
Methallylescaline
Proscaline
Psi-2C-T-4
TCB-2
Stimulants: Phenylethanolamine
Hordenine
Phenethylamine
Phenpromethamine
α-Methylphenethylamine (amphetamine)
β-Methylphenethylamine
m -Methylphenethylamine
N -Methylphenethylamine
o -Methylphenethylamine
p -Methylphenethylamine
Methylphenidate
Amphetamines Phentermines Cathinones Phenylisobutylamines
Entactogens: 4-CAB
4-MAB
Ariadne
BDB
Butylone
EBDB
Eutylone
MBDB Stimulants: Phenylisobutylamine
Phenylalkylpyrrolidines Catecholamines (and close relatives) Miscellaneous