Morazone
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Routes of administration | Oral, SC, IM[1] |
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ECHA InfoCard | 100.026.771 |
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Formula | C23H27N3O2 |
Molar mass | 377.488 g·mol−1 |
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Morazone (Novartrina, Orsimon, Rosimon-Neu, Tarcuzate) is a nonsteroidal anti-inflammatory drug (NSAID), originally developed by the German pharmaceutical company Ravensberg in the 1950s, which is used as an analgesic.[1][2][3] It produces phenmetrazine as a major metabolite and has been reported to have been abused as a recreational drug in the past.[4][5][6][7]
See also[]
- Famprofazone
- Morforex
References[]
- ^ a b Seyffart G (1991). Drug dosage in Renal Insufficiency. Boston: Kluwer Academic Publishers. p. 399. ISBN 978-0-7923-0964-2.
- ^ US patent 2943022, Siemer, H. & Doppstadt, A., "Substituted 1-phenyl-2,3-dimethyl-4-morpholino methyl pyrazolone-(5) Compounds and Process of Making Same", issued 1960-06-28, assigned to Ravensberg
- ^ Buckingham J, ed. (1996). Dictionary of Organic Compounds. Vol. 7. London: Chapman & Hall. p. 4659. ISBN 978-0-412-54090-5.
- ^ Bohn G, Rücker G, Kröger H (June 1976). "[Investigations of the decomposition and detection of morazone by thin-layer- and gas-liquid-chromatography]". Archives of Toxicology. 35 (3): 213–20. doi:10.1007/bf00293569. PMID 989292.
- ^ Neugebauer M (1984). "Some new urinary metabolites of famprofazone and morazone in man". Journal of Pharmaceutical and Biomedical Analysis. 2 (1): 53–60. doi:10.1016/0731-7085(84)80089-8. PMID 16867765.
- ^ Kingreen JC, Breger G (May 1984). "[Pellagra in morazone abuse]". Zeitschrift für Hautkrankheiten. 59 (9): 573–7. PMID 6145264.
- ^ Daunderer M, Janzen W (1972). "[ROSIMON-NEU--a non-prescription analgesic on the adolescent drug scene]". Beiträge zur Gerichtlichen Medizin. 29: 138–43. PMID 5081964.
Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA) | |
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pyrazolones / pyrazolidines |
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salicylates |
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acetic acid derivatives and related substances |
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oxicams |
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propionic acid derivatives (profens) |
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n-arylanthranilic acids (fenamates) |
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COX-2 inhibitors (coxibs) |
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other |
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NSAID combinations |
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Key: underline indicates initially developed first-in-class compound of specific group; #WHO-Essential Medicines; †withdrawn drugs; ‡veterinary use. | |
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ATC code: N06B |
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See also: Receptor/signaling modulators • Monoamine reuptake inhibitors • Adrenergics • Dopaminergics • Serotonergics • Monoamine metabolism modulators • Monoamine neurotoxins |
Phenethylamines | |
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Cathinones |
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Catecholamines (and close relatives) |
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Categories:
- Drugs not assigned an ATC code
- Substituted amphetamines
- Phenylmorpholines
- Nonsteroidal anti-inflammatory drugs
- Pyrazolones
- Stimulants
- Norepinephrine-dopamine releasing agents
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