Cellulose synthase (GDP-forming)
cellulose synthase (GDP-forming) | |||
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Identifiers | |||
EC no. | 2.4.1.29 | ||
CAS no. | 9027-18-3 | ||
Databases | |||
IntEnz | IntEnz view | ||
BRENDA | BRENDA entry | ||
ExPASy | NiceZyme view | ||
KEGG | KEGG entry | ||
MetaCyc | metabolic pathway | ||
PRIAM | profile | ||
PDB structures | RCSB PDB PDBe PDBsum | ||
Gene Ontology | AmiGO / QuickGO | ||
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In enzymology, a cellulose synthase (GDP-forming) (EC 2.4.1.29) is an enzyme that catalyzes the chemical reaction
- GDP-glucose + (1,4-beta-D-glucosyl)n GDP + (1,4-beta-D-glucosyl)n+1
Thus, the two substrates of this enzyme are and (1,4-beta-D-glucosyl)n, whereas its two products are GDP and (1,4-beta-D-glucosyl)n+1.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase. Other names in common use include cellulose synthase (guanosine diphosphate-forming), cellulose synthetase, guanosine diphosphoglucose-1,4-beta-glucan glucosyltransferase, and guanosine diphosphoglucose-cellulose glucosyltransferase. This enzyme participates in .
As of August 2019, no proteins with this activity are known in the UniProt/NiceZYme or the gene ontology database.
References[]
- Chambers J, Elbein AD (1970). "Biosynthesis of glucans in mung bean seedlings. Formation of beta-(1,4)-glucans from GDP-glucose and beta-(1,3)-glucans from UDP-glucose". Arch. Biochem. Biophys. 138 (2): 620–31. doi:10.1016/0003-9861(70)90389-9. PMID 4317490.
- Flowers HM, Batra KK, Kemp J, Hassid WZ (1969). "Biosynthesis of cellulose in vitro from guanosine diphosphate D-glucose with enzymic preparations from Phaseolus aureus and Lupinus albus". J. Biol. Chem. 244 (18): 4969–74. PMID 5824571.
- EC 2.4.1
- Enzymes of unknown structure
- EC 2.4 stubs