Homeobox C12 is a protein that in humans is encoded by the HOXC12 gene.[5]
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12.[5]
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Acampora D, D'Esposito M, Faiella A, Pannese M, Migliaccio E, Morelli F, Stornaiuolo A, Nigro V, Simeone A, Boncinelli E (December 1989). "The human HOX gene family". Nucleic Acids Research. 17 (24): 10385–402. doi:10.1093/nar/17.24.10385. PMC335308. PMID2574852.
Flagiello D, Gibaud A, Dutrillaux B, Poupon MF, Malfoy B (October 1997). "Distinct patterns of all-trans retinoic acid dependent expression of HOXB and HOXC homeogenes in human embryonal and small-cell lung carcinoma cell lines". FEBS Letters. 415 (3): 263–7. doi:10.1016/S0014-5793(97)01118-6. PMID9357979. S2CID26075369.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.