Pentifylline

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Pentifylline
Clinical data

Other names	1-Hexyltheophylline
ATC code	C04AD01 (WHO)
Identifiers
IUPAC name 1-Hexyl-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione
CAS Number	1028-33-7^Y
PubChem CID	70569
ChemSpider	63738^N
UNII	MBM1C4K26S
KEGG	D07174^Y
CompTox Dashboard (EPA)	DTXSID2057609
ECHA InfoCard	100.012.584
Chemical and physical data
Formula	C₁₃H₂₀N₄O₂
Molar mass	264.329 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCCCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C
InChI InChI=1S/C13H20N4O2/c1-4-5-6-7-8-17-12(18)10-11(14-9-15(10)2)16(3)13(17)19/h9H,4-8H2,1-3H3^N Key:MRWQRJMESRRJJB-UHFFFAOYSA-N^N
^NY (what is this?)

Pentifylline (marketed as Cosaldon) is a vasodilator.^[1]

References[]

^ Bath PM, Bath-Hextall FJ (2004). "Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke". The Cochrane Database of Systematic Reviews (3): CD000162. doi:10.1002/14651858.CD000162.pub2. PMID 15266424.

v t Peripheral vasodilators (C04)
Phenylethanolamine derivatives	Isoxsuprine Buphenine Bamethan
Alpha blockers	Non-selective Buflomedil Phentolamine Phenoxybenzamine Tolazoline Selective α₁-blockers Alfuzosin Doxazosin Prazosin Silodosin Tamsulosin Terazosin
Niacin and derivatives	Niacin Nicotinyl alcohol Inositol nicotinate Ciclonicate
Purine derivatives	Pentifylline Xantinol nicotinate Pentoxifylline Etofylline nicotinate
Ergot alkaloids	Ergoloid Nicergoline Dihydroergocristine
Other peripheral vasodilators	Cyclandelate Vincamine Moxisylyte Bencyclane Vinburnine Sulcotidil Naftidrofuryl Butalamine Visnadine Cetiedil Cinepazide Ifenprodil Azapetine Fasudil

v t Phosphodiesterase inhibitors
PDE1	MMPX SCH-51866 Vinpocetine
PDE2	BAY 60-7550 EHNA Oxindole
PDE3	Adibendan Amrinone (inamrinone) Anagrelide Bucladesine Cilostamide Cilostazol Enoximone KMUP-1 Milrinone Olprinone Pimobendan Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine
PDE4	Apremilast Arofylline Atizoram CC-1088 Cilomilast Crisaborole Drotaverine Etazolate Filaminast Glaucine HT-0712 ICI-63197 Irsogladine Luteolin Mesembrenone Mesembrine Piclamilast Roflumilast Rolipram RPL-554 YM-976 Zardaverine
PDE5	Acetildenafil Aildenafil Avanafil Benzamidenafil Icariin Homosildenafil Lodenafil Mirodenafil MY-5445 Nitrosoprodenafil SCH-51866 Sildenafil Sulfoaildenafil T-0156 Tadalafil Udenafil Vardenafil
PDE7	BRL-50481
PDE9	BAY 73-6691 Paraxanthine
PDE10	Mardepodect Papaverine Tofisopam
PDE11
Non-selective	Aminophylline Caffeine Choline theophyllinate CPX Dipyridamole Doxofylline Enprofylline Ibudilast IBMX Luteolin Pentoxifylline Propentofylline Theobromine Theophylline Zaprinast
Unsorted	Diazepam Diprophylline DPCPX Furafylline Lisofylline Moxaverine Pentifylline Proxyphylline Quercetin Trapidil
See also: Receptor/signaling modulators

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